Detalhe da pesquisa
1.
SAR340835, a Novel Selective Na+/Ca2+ Exchanger Inhibitor, Improves Cardiac Function and Restores Sympathovagal Balance in Heart Failure.
J Pharmacol Exp Ther
; 377(2): 293-304, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33602875
2.
Potential Therapeutic Value of Urotensin II Receptor Antagonist in Chronic Kidney Disease and Associated Comorbidities.
J Pharmacol Exp Ther
; 374(1): 24-37, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32332113
3.
A Proof-of-Concept Evaluation of JTPc and Tp-Tec as Proarrhythmia Biomarkers in Preclinical Species: A Retrospective Analysis by an HESI-Sponsored Consortium.
Int J Toxicol
; 38(1): 23-32, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-30567462
4.
Delimitation of the embryonic thermosensitive period for sex determination using an embryo growth model reveals a potential bias for sex ratio prediction in turtles.
J Therm Biol
; 73: 32-40, 2018 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-29549989
5.
Reminiscing about Jan Evangelista Purkinje: a pioneer of modern experimental physiology.
Adv Physiol Educ
; 41(4): 528-538, 2017 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29066603
6.
Dispersal evolution and resource matching in a spatially and temporally variable environment.
J Theor Biol
; 370: 184-96, 2015 Apr 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-25637766
7.
Safety pharmacology--current and emerging concepts.
Toxicol Appl Pharmacol
; 273(2): 229-41, 2013 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23732082
8.
A spatially explicit model of sex ratio evolution in response to sex-biased dispersal.
Theor Popul Biol
; 80(2): 141-9, 2011 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-21570994
9.
Time for a Fully Integrated Nonclinical-Clinical Risk Assessment to Streamline QT Prolongation Liability Determinations: A Pharma Industry Perspective.
Clin Pharmacol Ther
; 109(2): 310-318, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32866317
10.
The antimalarial MMV688533 provides potential for single-dose cures with a high barrier to Plasmodium falciparum parasite resistance.
Sci Transl Med
; 13(603)2021 07 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-34290058
11.
Recent advances on the estimation of the thermal reaction norm for sex ratios.
PeerJ
; 8: e8451, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32181050
12.
Temperature-dependent sex determination and global change: are some species at greater risk?
Oecologia
; 160(3): 493-506, 2009 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-19277719
13.
Human organotypic bioconstructs from organ-on-chip devices for human-predictive biological insights on drug candidates.
Expert Opin Drug Saf
; 18(8): 651-677, 2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31268355
14.
Identification of Ion Currents Components Generating Field Potential Recorded in MEA From hiPSC-CM.
IEEE Trans Biomed Eng
; 65(6): 1311-1319, 2018 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28880155
15.
In vitro secondary pharmacological profiling: An IQ-DruSafe industry survey on current practices.
J Pharmacol Toxicol Methods
; 93: 7-14, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-30030184
16.
Cross-Site Reliability of Human Induced Pluripotent stem cell-derived Cardiomyocyte Based Safety Assays Using Microelectrode Arrays: Results from a Blinded CiPA Pilot Study.
Toxicol Sci
; 164(2): 550-562, 2018 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29718449
17.
Female philopatry in a heterogeneous environment: ordinary conditions leading to extraordinary ESS sex ratios.
BMC Evol Biol
; 7: 13, 2007 Feb 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-17284311
18.
An evaluation of the utility of LVdP/dt40, QA interval, LVdP/dtmin and Tau as indicators of drug-induced changes in contractility and lusitropy in dogs.
J Pharmacol Toxicol Methods
; 85: 1-21, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28065821
19.
Comprehensive in vitro Proarrhythmia Assay (CiPA): Pending issues for successful validation and implementation.
J Pharmacol Toxicol Methods
; 81: 21-36, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27233533
20.
Comment on: Carter AW, Paitz RT, Bowden RM. 2019. The Devil is in the Details: Identifying Aspects of Temperature Variation that Underlie Sex Determination in Species with TSD. Integrative and Comparative Biology 59:1081-8.
Integr Comp Biol
; 60(6): 1347-1350, 2020 12 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-33031498