Abnormal visual scanning and impaired mental state recognition in pre-manifest Huntington disease.

Huntington's disease (HD) is a genetic neurodegenerative disorder that affects not only the motor but also the cognitive and the neuropsychiatric domain. In particular, deficits in mental state recognition may emerge already at early pre-manifest stages of the disease. The aim of this research was to explore the relation between visual scanning behavior and complex mental state recognition in individuals with pre-manifest HD (preHD). Eighteen preHD and eighteen age- and gender-matched healthy controls took the revised "Reading the Mind in the Eyes" test while their eye-movements were tracked. In addition to the expected deficits in mental state recognition, preHD showed abnormalities concerning all three scanning variables we considered, namely the absolute number of fixations (FC), the average fixation duration (AFD), and the percentage of time spent fixating (FTR). In preHD, FC and FTR but not AFD predicted mental state recognition over and beyond general disease-related declines in cognition and motor functioning. Notably, preHD showed abnormal vertical and horizontal fixation patterns, and these patterns predicted mental state recognition, suggesting the involvement of mechanisms related to the embodied processing of emotional stimuli. Overall, our results suggest that impaired facial mental state recognition in pre-manifest HD is partly due to emotional-motivational factors affecting the visual scanning of facial expressions.

From "Einfühlung" to empathy: exploring the relationship between aesthetic and interpersonal experience.

Is there a relationship between aesthetic and interpersonal experience? This question is motivated not only by the fact that historically experiences of both kinds have often been accounted for in terms of "empathy", the English translation of the German term "Einfühlung", but also by the fact that some contemporary theories refer to mechanisms underlying both aesthetic and interpersonal experience. In this Editorial introducing the special section titled "From 'Einfühlung' to empathy: exploring the relationship between aesthetic and interpersonal experience", we briefly sketch these two motivations and the relationship between the different mechanisms that have been associated with both aesthetic and interpersonal experience.

The relationship between 'theory of mind' and attachment-related anxiety and avoidance in Italian adolescents.

This study examined the relationship between 'theory of mind' and attachment-related anxiety and avoidance in adolescence. The "Reading the Mind in the Eyes" test and the "Experiences in Close Relationships - Relationship Structures" questionnaires were administered to 402 14-19 year-old adolescents. Contrary to expectations, anxiety but not avoidance with mother was associated with less accurate mindreading, and this effect was stronger in younger than in older adolescents. Results might be explained in terms of the inconsistency of caregiver behavior that is supposed to cause anxious strategies, and thus illustrate the need to consider not only the effects, but also the causes of different types of insecure strategies.

Are anxiously attached women better mindreaders?

This research was aimed at providing first evidence concerning the relationship between adults' self-reported attachment style and their performance on a standard 'theory of mind' task. Based on adult attachment theory, we hypothesized that the two dimensions of self-reported adult attachment, anxiety and avoidance, are differently related to 'theory of mind,' and that this relationship is moderated by variables concerning the 'theory of mind' stimuli. The 'Experiences in Close Relationships' questionnaire and the 'Reading the Mind in the Eyes' test were administered to 132 young women. In line with our expectations, women's attachment-related anxiety was associated with better mind reading concerning stimuli that were emotionally neutral or difficult to recognize.

West vs. West like East vs. West? A comparison between Italian and US American context sensitivity and Fear of Isolation.

Easterners tend to process information more holistically than Westerners. Kim and Markman (J Exp Soc Psychol 42(3):350-364, 2006) suggest that these differences are rooted in higher chronic levels of Fear of Isolation (FOI) for those cultures that process information more holistically. The goal of this study was to determine if these differences and their suggested cause could be found with two different Western cultures. Testing Italian (IT) and US American (US) adults, we found that IT participants processed information more holistically and had a higher chronic level of FOI than US participants; furthermore, the manipulation of FOI affected context sensitivity more for IT than for US participants. The results demonstrate that IT participants were more similar to previous research with Eastern populations than with Western populations (Kim and Markman in J Exp Soc Psychol 42(3):350-364, 2006) and indicate a within-Western culture difference for reasoning styles and support the hypothesis that this difference is due to different chronic levels of FOI.

Cross-cultural differences in intercultural mindreading: Evidence from a sample of Palestinian, Italian, and German adolescents.

Despite the fact that the "Reading the Mind in the Eyes" Test (RMET) is now available in more than 20 languages, there are only very few cross-cultural researchers using this test, and these researchers generally focus on North American versus East Asian cultures. Considering that the RMET stimuli were selected and constructed in the United Kingdom, this research explored cross-cultural differences in intercultural mindreading with a large sample of adolescents from Palestine (PAL), Italy (ITA), and Germany (GER). In addition to significant main effects of age (younger < older) and gender (male < female), we found a significant main effect of country (PAL < ITA < GER) and a significant interaction between gender and country. Individualism was not related to mindreading in any of the three countries whereas collectivism was positively related in PAL, but not in ITA or GER, accounting only for a very small amount of the variance. Our results suggest that (a) there may be cultural ingroup effects on mindreading, (b) the known female superiority in mindreading may be moderated by cultural factors, and (c) depending on cultural factors, individualism and collectivism may be differently related to mindreading.

Emotion recognition and inhibitory control in manifest and pre-manifest Huntington's disease: evidence from a new Stroop task.

Huntington's disease (HD) is a genetic neurodegenerative disorder that affects not only the motor but also the cognitive domain. In particular, cognitive symptoms such as impaired executive skills and deficits in recognizing other individuals' mental state may emerge many years before the motor symptoms. This study was aimed at testing two cognitive hypotheses suggested by previous research with a new Stroop task created for the purpose: 1) the impairment of emotion recognition in HD is moderated by the emotions' valence, and 2) inhibitory control is impaired in HD. Forty manifest and 20 pre-manifest HD patients and their age- and gender-matched controls completed both the traditional "Stroop Color and Word Test" (SCWT) and the newly created "Stroop Emotion Recognition under Word Interference Task" (SERWIT), which consist in 120 photographs of sad, calm, or happy faces with either congruent or incongruent word interference. On the SERWIT, impaired emotion recognition in manifest HD was moderated by emotion type, with deficits being larger in recognizing sadness and calmness than in recognizing happiness, but it was not moderated by stimulus congruency. On the SCWT, six different interference scores yielded as many different patterns of group effects. Overall our results corroborate the hypothesis that impaired emotion recognition in HD is moderated by the emotions' valence, but do not provide evidence for the hypothesis that inhibitory control is impaired in HD. Further research is needed to learn more about the psychological mechanisms underlying the moderating effect of emotional valence on impaired emotion recognition in HD, and to corroborate the hypothesis that the inhibitory processes involved in Stroop tasks are not impaired in HD. Looking beyond this study, the SERWIT promises to make important contributions to disentangling the cognitive and the psychomotor aspects of neurological disorders. The research was approved by the Ethics Committee of the "Istituto Leonarda Vaccari", Rome on January 24, 2018.

Effects of information type on children's interrogative suggestibility: is Theory-of-Mind involved?

This research was aimed at learning more about the different psychological mechanisms underlying children's suggestibility to leading questions, on the one hand, and children's suggestibility to negative feedback, on the other, by distinguishing between interview questions concerning different types of information. Results showed that, unlike the developmental pattern of children's suggestibility to leading questions, the developmental pattern of children's suggestibility to negative feedback differed depending on whether the interview questions concerned external facts (physical states and events) or internal facts (mental states and events). This difference was not manifested in response to questions concerning central versus peripheral facts. Results are interpreted in terms of the hypothesis that children's suggestibility to negative feedback is differently affected by "Theory-of-Mind" abilities than children's suggestibility to leading questions. Further research is needed in order to test this hypothesis.

Questioning the dichotomy between vegetative state and minimally conscious state: a review of the statistical evidence.

Given the enormous consequences that the diagnosis of vegetative state (VS) vs. minimally conscious state (MCS) may have for the treatment of patients with disorders of consciousness, it is particularly important to empirically legitimate the distinction between these two discrete levels of consciousness. Therefore, the aim of this contribution is to review all the articles reporting statistical evidence concerning the performance of patients in VS vs. patients in MCS, on behavioral or neurophysiological measures. Twenty-three articles matched these inclusion criteria, and comprised behavioral, electroencephalographic (EEG), positron emission tomography (PET) and magnetic resonance imaging (MRI) measures. The analysis of these articles yielded 47 different statistical findings. More than half of these findings (n = 24) did not reveal any statistically significant difference between VS and MCS. Overall, there was no combination of variables that allowed reliably discriminating between VS and MCS. This pattern of results casts doubt on the empirical validity of the distinction between VS and MCS.