Detalhe da pesquisa
1.
The impact of coding germline variants on contralateral breast cancer risk and survival.
Am J Hum Genet
; 110(3): 475-486, 2023 03 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36827971
2.
Implementing mainstream genetic counseling within the area-wide network of the German Consortium Hereditary Breast and Ovarian Cancer (GC-HBOC): Satisfaction of primary care providers with the provided state-of-the-art training by the Cologne Center.
J Genet Couns
; 33(1): 206-215, 2024 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38351721
3.
A likelihood ratio approach for utilizing case-control data in the clinical classification of rare sequence variants: application to BRCA1 and BRCA2.
Hum Mutat
; 20232023.
Artigo
em Inglês
| MEDLINE | ID: mdl-38725546
4.
Ovarian cancer onset across different BRCA mutation types: a view to a more tailored approach for BRCA mutated patients.
Int J Gynecol Cancer
; 33(2): 257-262, 2023 02 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36581488
5.
AGO-OVAR 28/ENGOT-ov57. Niraparib alone versus niraparib in combination with bevacizumab in patients with carboplatin-taxane-based chemotherapy in advanced ovarian cancer: a multicenter randomized phase III trial.
Int J Gynecol Cancer
; 33(12): 1966-1969, 2023 Dec 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-37935524
6.
Sensitivity and specificity of loss of heterozygosity analysis for the classification of rare germline variants in BRCA1/2: results of the observational AGO-TR1 study (NCT02222883).
J Med Genet
; 59(3): 248-252, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33273034
7.
Effect of HIPEC according to HRD/BRCAwt genomic profile in stage III ovarian cancer: Results from the phase III OVHIPEC trial.
Int J Cancer
; 151(8): 1394-1404, 2022 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35583992
8.
Polygenic risk scores indicate extreme ages at onset of breast cancer in female BRCA1/2 pathogenic variant carriers.
BMC Cancer
; 22(1): 706, 2022 Jun 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-35761208
9.
Clinical and molecular characteristics of HER2-low-positive breast cancer: pooled analysis of individual patient data from four prospective, neoadjuvant clinical trials.
Lancet Oncol
; 22(8): 1151-1161, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34252375
10.
The predictive ability of the 313 variant-based polygenic risk score for contralateral breast cancer risk prediction in women of European ancestry with a heterozygous BRCA1 or BRCA2 pathogenic variant.
Genet Med
; 23(9): 1726-1737, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34113011
11.
[HerediCaRe: Documentation and IT Solution of a Specialized Registry for Hereditary Breast and Ovarian Cancer]. / HerediCaRe: Dokumentations- und IT-Lösung eines spezialisierten Registers für erblichen Brust- und Eierstockkrebs.
Gesundheitswesen
; 83(S 01): S12-S17, 2021 Nov.
Artigo
em Alemão
| MEDLINE | ID: mdl-34731888
12.
Breast cancer risk in BRCA1/2 mutation carriers and noncarriers under prospective intensified surveillance.
Int J Cancer
; 146(4): 999-1009, 2020 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31081934
13.
Deleterious somatic variants in 473 consecutive individuals with ovarian cancer: results of the observational AGO-TR1 study (NCT02222883).
J Med Genet
; 56(9): 574-580, 2019 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-30979843
14.
Large scale multifactorial likelihood quantitative analysis of BRCA1 and BRCA2 variants: An ENIGMA resource to support clinical variant classification.
Hum Mutat
; 40(9): 1557-1578, 2019 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31131967
15.
Germline loss-of-function variants in the BARD1 gene are associated with early-onset familial breast cancer but not ovarian cancer.
Breast Cancer Res
; 21(1): 55, 2019 04 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-31036035
16.
Investigating the effects of additional truncating variants in DNA-repair genes on breast cancer risk in BRCA1-positive women.
BMC Cancer
; 19(1): 787, 2019 Aug 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31395037
17.
Benchmarking of a checklist for the identification of familial risk for breast and ovarian cancers in a prospective cohort.
Breast J
; 25(3): 455-460, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30953388
18.
Diagnosis of Li-Fraumeni Syndrome: Differentiating TP53 germline mutations from clonal hematopoiesis: Results of the observational AGO-TR1 trial.
Hum Mutat
; 39(12): 2040-2046, 2018 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30216591
19.
An evaluation of the challenges to developing tumor BRCA1 and BRCA2 testing methodologies for clinical practice.
Hum Mutat
; 39(3): 394-405, 2018 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29215764
20.
BRIP1 loss-of-function mutations confer high risk for familial ovarian cancer, but not familial breast cancer.
Breast Cancer Res
; 20(1): 7, 2018 01 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-29368626