Detalhe da pesquisa
1.
A novel antibiotic class targeting the lipopolysaccharide transporter.
Nature
; 625(7995): 566-571, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-38172634
2.
A novel mechanism-based pharmacokinetic-pharmacodynamic (PKPD) model describing ceftazidime/avibactam efficacy against ß-lactamase-producing Gram-negative bacteria.
J Antimicrob Chemother
; 75(2): 400-408, 2020 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31670804
3.
Nacubactam Enhances Meropenem Activity against Carbapenem-Resistant Klebsiella pneumoniae Producing KPC.
Antimicrob Agents Chemother
; 63(8)2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31182530
4.
Activity of nacubactam (RG6080/OP0595) combinations against MBL-producing Enterobacteriaceae.
J Antimicrob Chemother
; 74(4): 953-960, 2019 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30590470
5.
Escape mutations circumvent a tradeoff between resistance to a beta-lactam and resistance to a beta-lactamase inhibitor.
Nat Commun
; 11(1): 2029, 2020 04 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-32332717
6.
Efficacy of iclaprim against wild-type and thymidine kinase-deficient methicillin-resistant Staphylococcus aureus isolates in an in vitro fibrin clot model.
Antimicrob Agents Chemother
; 53(9): 3635-41, 2009 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-19564362
7.
Increased hydrophobic interactions of iclaprim with Staphylococcus aureus dihydrofolate reductase are responsible for the increase in affinity and antibacterial activity.
J Antimicrob Chemother
; 63(4): 687-98, 2009 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-19211577
8.
Escherichia coli phnN, encoding ribose 1,5-bisphosphokinase activity (phosphoribosyl diphosphate forming): dual role in phosphonate degradation and NAD biosynthesis pathways.
J Bacteriol
; 185(9): 2793-801, 2003 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-12700258