Detalhe da pesquisa
1.
The Subtype Selectivity in Search of Potent Hypotensive Agents among 5,5-Dimethylhydantoin Derived α1-Adrenoceptors Antagonists.
Int J Mol Sci
; 24(23)2023 Nov 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-38068933
2.
New Triazine Derivatives as Serotonin 5-HT6 Receptor Ligands.
Molecules
; 28(3)2023 Jan 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-36770774
3.
Relationships between Molecular Characteristics of Novel Organic Selenium Compounds and the Formation of Sulfur Compounds in Selenium Biofortified Kale Sprouts.
Molecules
; 28(5)2023 Feb 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-36903308
4.
An exit beyond the pharmacophore model for 5-HT6R agents - a new strategy to gain dual 5-HT6/5-HT2A action for triazine derivatives with procognitive potential.
Bioorg Chem
; 121: 105695, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35228010
5.
Structure Prediction, Evaluation, and Validation of GPR18 Lipid Receptor Using Free Programs.
Int J Mol Sci
; 23(14)2022 Jul 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-35887268
6.
Multitargeting the Action of 5-HT6 Serotonin Receptor Ligands by Additional Modulation of Kinases in the Search for a New Therapy for Alzheimer's Disease: Can It Work from a Molecular Point of View?
Int J Mol Sci
; 23(15)2022 Aug 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35955902
7.
2-{5-[(Z,2Z)-2-Chloro-3-(4-nitrophenyl)-2-propenylidene]-4-oxo-2-thioxothiazolidin-3-yl}-3-methylbutanoic Acid as a Potential Anti-Breast Cancer Molecule.
Int J Mol Sci
; 23(8)2022 Apr 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35456915
8.
Benzophenone Derivatives with Histamine H3 Receptor Affinity and Cholinesterase Inhibitory Potency as Multitarget-Directed Ligands for Possible Therapy of Alzheimer's Disease.
Molecules
; 28(1)2022 Dec 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-36615435
9.
Chemical update on the potential for serotonin 5-HT6 and 5-HT7 receptor agents in the treatment of Alzheimer's disease.
Bioorg Med Chem Lett
; 49: 128275, 2021 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34311086
10.
The relationship between stereochemical and both, pharmacological and ADME-Tox, properties of the potent hydantoin 5-HT7R antagonist MF-8.
Bioorg Chem
; 106: 104466, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33246603
11.
An insight into the structure of 5-spiro aromatic derivatives of imidazolidine-2,4-dione, a new group of very potent inhibitors of tumor multidrug resistance in T-lymphoma cells.
Bioorg Chem
; 109: 104735, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33640632
12.
Cyanobiphenyls: Novel H3 receptor ligands with cholinesterase and MAO B inhibitory activity as multitarget compounds for potential treatment of Alzheimer's disease.
Bioorg Chem
; 114: 105129, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34217977
13.
Low Basicity as a Characteristic for Atypical Ligands of Serotonin Receptor 5-HT2.
Int J Mol Sci
; 22(3)2021 Jan 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-33494248
14.
Novel N-Substituted 3-Aryl-4-(diethoxyphosphoryl)azetidin-2-ones as Antibiotic Enhancers and Antiviral Agents in Search for a Successful Treatment of Complex Infections.
Int J Mol Sci
; 22(15)2021 Jul 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-34360797
15.
The Phenoxyalkyltriazine Antagonists for 5-HT6 Receptor with Promising Procognitive and Pharmacokinetic Properties In Vivo in Search for a Novel Therapeutic Approach to Dementia Diseases.
Int J Mol Sci
; 22(19)2021 Oct 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-34639113
16.
Molecular Insights into an Antibiotic Enhancer Action of New Morpholine-Containing 5-Arylideneimidazolones in the Fight against MDR Bacteria.
Int J Mol Sci
; 22(4)2021 Feb 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-33669790
17.
The Structural Determinants for α1-Adrenergic/Serotonin Receptors Activity among Phenylpiperazine-Hydantoin Derivatives.
Molecules
; 26(22)2021 Nov 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-34834117
18.
N-Skatyltryptamines-Dual 5-HT6R/D2R Ligands with Antipsychotic and Procognitive Potential.
Molecules
; 26(15)2021 Jul 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-34361754
19.
In silico and in vitro studies on interaction of novel non-imidazole histamine H3R antagonists with CYP3A4.
Bioorg Med Chem Lett
; 30(11): 127147, 2020 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32249114
20.
N-Substituted piperazine derivatives as potential multitarget agents acting on histamine H3 receptor and cancer resistance proteins.
Bioorg Med Chem Lett
; 30(22): 127522, 2020 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32871268