Detalhe da pesquisa
1.
Involvement of γ-Glutamyl Transpeptidase in Ischemia/Reperfusion-Induced Cardiac Dysfunction in Isolated Rat Hearts.
Biol Pharm Bull
; 42(11): 1947-1952, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31685777
2.
Synthesis and inhibitory activity of mechanism-based 4-coumaroyl-CoA ligase inhibitors.
Bioorg Med Chem
; 26(9): 2466-2474, 2018 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29685682
3.
Synthesis and evaluation of the inhibitory activity of the four stereoisomers of the potent and selective human γ-glutamyl transpeptidase inhibitor GGsTop.
Bioorg Med Chem Lett
; 27(21): 4920-4924, 2017 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28985998
4.
Structural basis for gating mechanisms of a eukaryotic P-glycoprotein homolog.
Proc Natl Acad Sci U S A
; 111(11): 4049-54, 2014 Mar 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-24591620
5.
Cystathionine is a novel substrate of cystine/glutamate transporter: implications for immune function.
J Biol Chem
; 290(14): 8778-88, 2015 Apr 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-25713140
6.
GGsTop, a novel and specific γ-glutamyl transpeptidase inhibitor, protects hepatic ischemia-reperfusion injury in rats.
Am J Physiol Gastrointest Liver Physiol
; 311(2): G305-12, 2016 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27365338
7.
Phosphonate-based irreversible inhibitors of human γ-glutamyl transpeptidase (GGT). GGsTop is a non-toxic and highly selective inhibitor with critical electrostatic interaction with an active-site residue Lys562 for enhanced inhibitory activity.
Bioorg Med Chem
; 24(21): 5340-5352, 2016 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27622749
8.
Crystal structures of ß-primeverosidase in complex with disaccharide amidine inhibitors.
J Biol Chem
; 289(24): 16826-34, 2014 Jun 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-24753293
9.
Structure of Bacillus subtilis γ-glutamyltranspeptidase in complex with acivicin: diversity of the binding mode of a classical and electrophilic active-site-directed glutamate analogue.
Acta Crystallogr D Biol Crystallogr
; 70(Pt 2): 607-14, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24531494
10.
Glutathione-analogous peptidyl phosphorus esters as mechanism-based inhibitors of γ-glutamyl transpeptidase for probing cysteinyl-glycine binding site.
Bioorg Med Chem
; 22(3): 1176-94, 2014 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24411479
11.
Occurrence of a bacterial membrane microdomain at the cell division site enriched in phospholipids with polyunsaturated hydrocarbon chains.
J Biol Chem
; 287(29): 24113-21, 2012 Jul 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-22648406
12.
Enhancement of production of eugenol and its glycosides in transgenic aspen plants via genetic engineering.
Biochem Biophys Res Commun
; 436(1): 73-8, 2013 Jun 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-23707945
13.
A detailed biochemical characterization of phosphopantothenate synthetase, a novel enzyme involved in coenzyme A biosynthesis in the Archaea.
Extremophiles
; 16(6): 819-28, 2012 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-22940806
14.
A sulfoximine-based inhibitor of human asparagine synthetase kills L-asparaginase-resistant leukemia cells.
Bioorg Med Chem
; 20(19): 5915-27, 2012 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22951255
15.
Structural basis for the spectral difference in luciferase bioluminescence.
Nature
; 440(7082): 372-6, 2006 Mar 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-16541080
16.
Characterization of raspberry ketone/zingerone synthase, catalyzing the alpha, beta-hydrogenation of phenylbutenones in raspberry fruits.
Biochem Biophys Res Commun
; 412(1): 104-8, 2011 Aug 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-21802408
17.
Preventive effect of GGsTop, a novel and selective γ-glutamyl transpeptidase inhibitor, on ischemia/reperfusion-induced renal injury in rats.
J Pharmacol Exp Ther
; 339(3): 945-51, 2011 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-21937737
18.
Molecular design of spacer-N-linked sialoglycopolypeptide as polymeric inhibitors against influenza virus infection.
Biomacromolecules
; 10(7): 1894-903, 2009 Jul 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-19438195
19.
A critical electrostatic interaction mediates inhibitor recognition by human asparagine synthetase.
Bioorg Med Chem
; 17(18): 6641-50, 2009 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19683931
20.
Expression and biochemical characterization of beta-primeverosidase and application of beta-primeverosylamidine to affinity purification.
Biosci Biotechnol Biochem
; 72(2): 376-83, 2008 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-18256510