Detalhe da pesquisa
1.
Early Selection of the Amino Acid Alphabet Was Adaptively Shaped by Biophysical Constraints of Foldability.
J Am Chem Soc
; 145(9): 5320-5329, 2023 03 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-36826345
2.
In Vitro Evolution Reveals Noncationic Protein-RNA Interaction Mediated by Metal Ions.
Mol Biol Evol
; 39(3)2022 03 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-35137196
3.
CoLiDe: Combinatorial Library Design tool for probing protein sequence space.
Bioinformatics
; 37(4): 482-489, 2021 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32956450
4.
Sequence Versus Composition: What Prescribes IDP Biophysical Properties?
Entropy (Basel)
; 21(7)2019 Jul 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33267368
5.
Sequestration of a highly reactive intermediate in an evolving pathway for degradation of pentachlorophenol.
Proc Natl Acad Sci U S A
; 110(24): E2182-90, 2013 Jun 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-23676275
6.
High-throughput Selection of Human de novo-emerged sORFs with High Folding Potential.
Genome Biol Evol
; 16(4)2024 Apr 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38597156
7.
Experimental characterization of de novo proteins and their unevolved random-sequence counterparts.
Nat Ecol Evol
; 7(4): 570-580, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-37024625
8.
Pentachlorophenol hydroxylase, a poorly functioning enzyme required for degradation of pentachlorophenol by Sphingobium chlorophenolicum.
Biochemistry
; 51(18): 3848-60, 2012 May 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-22482720
9.
Peptides before and during the nucleotide world: an origins story emphasizing cooperation between proteins and nucleic acids.
J R Soc Interface
; 19(187): 20210641, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-35135297
10.
Modern and prebiotic amino acids support distinct structural profiles in proteins.
Open Biol
; 12(6): 220040, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35728622
11.
Structure and function of naturally evolved de novo proteins.
Curr Opin Struct Biol
; 68: 175-183, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33567396
12.
Enzyme catalysis prior to aromatic residues: Reverse engineering of a dephospho-CoA kinase.
Protein Sci
; 30(5): 1022-1034, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33739538
13.
Toxin rescue by a random sequence.
Nat Ecol Evol
; 7(12): 1963-1964, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37945945
14.
Structural insight into the pharmacophore pocket of human glutamate carboxypeptidase II.
J Med Chem
; 50(14): 3267-73, 2007 Jul 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-17567119
15.
Random protein sequences can form defined secondary structures and are well-tolerated in vivo.
Sci Rep
; 7(1): 15449, 2017 11 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-29133927
16.
Comparison of human glutamate carboxypeptidases II and III reveals their divergent substrate specificities.
FEBS J
; 283(13): 2528-45, 2016 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27208881
17.
Structural insight into the evolutionary and pharmacologic homology of glutamate carboxypeptidases II and III.
FEBS J
; 276(16): 4448-62, 2009 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-19678840
18.
Tissue expression and enzymologic characterization of human prostate specific membrane antigen and its rat and pig orthologs.
Prostate
; 68(2): 171-82, 2008 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18076021
19.
Structural basis of interactions between human glutamate carboxypeptidase II and its substrate analogs.
J Mol Biol
; 376(5): 1438-50, 2008 Mar 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-18234225
20.
Biochemical characterization of human glutamate carboxypeptidase III.
J Neurochem
; 101(3): 682-96, 2007 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-17241121