Detalhe da pesquisa
1.
Population pharmacokinetics of a novel PCSK9 antisense oligonucleotide.
Br J Clin Pharmacol
; 2024 Mar 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-38504437
2.
Cilia-localized LKB1 regulates chemokine signaling, macrophage recruitment, and tissue homeostasis in the kidney.
EMBO J
; 37(15)2018 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29925518
3.
Eomes cannot replace its paralog T-bet during expansion and differentiation of CD8 effector T cells.
PLoS Pathog
; 16(9): e1008870, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32991634
4.
Targeting inflammation for the treatment of Diabetic Kidney Disease: a five-compartment mechanistic model.
BMC Nephrol
; 23(1): 208, 2022 06 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-35698028
5.
The mitochondrial transporter SLC25A25 links ciliary TRPP2 signaling and cellular metabolism.
PLoS Biol
; 16(8): e2005651, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30080851
6.
HIF-1α drives cyst growth in advanced stages of autosomal dominant polycystic kidney disease.
Kidney Int
; 94(5): 849-851, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30348299
7.
Polycystic Kidney Disease with Hyperinsulinemic Hypoglycemia Caused by a Promoter Mutation in Phosphomannomutase 2.
J Am Soc Nephrol
; 28(8): 2529-2539, 2017 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-28373276
8.
Efficient genome editing of differentiated renal epithelial cells.
Pflugers Arch
; 469(2): 303-311, 2017 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27987038
9.
Targeted rescue of a polycystic kidney disease mutation by lysosomal inhibition.
Kidney Int
; 89(4): 949-55, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26924047
10.
N-glycosylation determines the abundance of the transient receptor potential channel TRPP2.
J Biol Chem
; 289(21): 14854-67, 2014 May 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-24719335
11.
The TRPP subfamily and polycystin-1 proteins.
Handb Exp Pharmacol
; 222: 675-711, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24756726
12.
Roxadustat and Oral Iron Absorption in Chinese Patients with Anemia of Chronic Kidney Disease: A Randomized, Open-Label, Phase 4 Study (ALTAI).
Adv Ther
; 41(3): 1168-1183, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38280066
13.
Single Gene Mutations in Pkd1 or Tsc2 Alter Extracellular Vesicle Production and Trafficking.
Biology (Basel)
; 11(5)2022 May 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35625437
14.
A case-study of model-informed drug development of a novel PCSK9 anti sense oligonucleotide. Part 1: First time in man to phase II.
CPT Pharmacometrics Syst Pharmacol
; 11(12): 1569-1577, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36126230
15.
Wildtype heterogeneity contributes to clonal variability in genome edited cells.
Sci Rep
; 12(1): 18211, 2022 10 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-36307508
16.
TRPP channels and polycystins.
Adv Exp Med Biol
; 704: 287-313, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-21290302
17.
Loss of PKD1/polycystin-1 impairs lysosomal activity in a CAPN (calpain)-dependent manner.
Autophagy
; 17(9): 2384-2400, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32967521
18.
Rapid target validation in a Cas9-inducible hiPSC derived kidney model.
Sci Rep
; 11(1): 16532, 2021 08 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-34400685
19.
Identification of pathological transcription in autosomal dominant polycystic kidney disease epithelia.
Sci Rep
; 11(1): 15139, 2021 07 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-34301992
20.
Author Correction: Eomes and Brachyury control pluripotency exit and germ-layer segregation by changing the chromatin state.
Nat Cell Biol
; 22(1): 135, 2020 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-31844271