Detalhe da pesquisa
1.
K-Ras Promotes Tumorigenicity through Suppression of Non-canonical Wnt Signaling.
Cell
; 163(5): 1237-1251, 2015 Nov 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-26590425
2.
Concurrent inhibition of oncogenic and wild-type RAS-GTP for cancer therapy.
Nature
; 629(8013): 919-926, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38589574
3.
Inhibition of Ras/Raf/MEK/ERK Pathway Signaling by a Stress-Induced Phospho-Regulatory Circuit.
Mol Cell
; 64(5): 875-887, 2016 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27889448
4.
KRAS G13D sensitivity to neurofibromin-mediated GTP hydrolysis.
Proc Natl Acad Sci U S A
; 116(44): 22122-22131, 2019 10 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-31611389
5.
New weapons to penetrate the armor: Novel reagents and assays developed at the NCI RAS Initiative to enable discovery of RAS therapeutics.
Semin Cancer Biol
; 54: 174-182, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29432816
6.
Homogeneous Dual-Parametric-Coupled Assay for Simultaneous Nucleotide Exchange and KRAS/RAF-RBD Interaction Monitoring.
Anal Chem
; 92(7): 4971-4979, 2020 04 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32106676
7.
Label-Free Time-Gated Luminescent Detection Method for the Nucleotides with Varying Phosphate Content.
Sensors (Basel)
; 18(11)2018 Nov 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-30453509
8.
Interferon-induced transmembrane protein 1 regulates endothelial lumen formation during angiogenesis.
Arterioscler Thromb Vasc Biol
; 34(5): 1011-9, 2014 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-24603679
9.
Translational and Therapeutic Evaluation of RAS-GTP Inhibition by RMC-6236 in RAS-Driven Cancers.
Cancer Discov
; : OF1-OF24, 2024 Apr 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-38593348
10.
RAS signaling: Divide and conquer.
Nat Chem Biol
; 13(1): 7-8, 2016 12 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-27984577
11.
Tumor-selective effects of active RAS inhibition in pancreatic ductal adenocarcinoma.
bioRxiv
; 2023 Dec 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-38105998
12.
Sensitivity of Oncogenic KRAS-Expressing Cells to CDK9 Inhibition.
SLAS Discov
; 26(7): 922-932, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33896272
13.
Targeted mass spectrometry-based assays enable multiplex quantification of receptor tyrosine kinase, MAP Kinase, and AKT signaling.
Cell Rep Methods
; 1(3)2021 07 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-34671754
14.
TNF primes endothelial cells for angiogenic sprouting by inducing a tip cell phenotype.
Blood
; 111(10): 4997-5007, 2008 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18337563
15.
Crosstalk between vascular endothelial growth factor, notch, and transforming growth factor-beta in vascular morphogenesis.
Circ Res
; 102(6): 637-52, 2008 Mar 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-18369162
16.
Efforts to Develop KRAS Inhibitors.
Cold Spring Harb Perspect Med
; 8(7)2018 07 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29101115
17.
The bacterial Ras/Rap1 site-specific endopeptidase RRSP cleaves Ras through an atypical mechanism to disrupt Ras-ERK signaling.
Sci Signal
; 11(550)2018 10 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30279169
18.
Cell-autonomous notch signaling regulates endothelial cell branching and proliferation during vascular tubulogenesis.
FASEB J
; 19(8): 1027-9, 2005 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-15774577
19.
Farnesylated and methylated KRAS4b: high yield production of protein suitable for biophysical studies of prenylated protein-lipid interactions.
Sci Rep
; 5: 15916, 2015 Nov 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-26522388
20.
Targeting RAF kinases for cancer therapy: BRAF-mutated melanoma and beyond.
Nat Rev Cancer
; 14(7): 455-67, 2014 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-24957944