The challenging management of Rift Valley Fever in humans: literature review of the clinical disease and algorithm proposal.

Rift Valley Fever (RVF) is an emerging zoonotic arbovirus with a complex cycle of transmission that makes difficult the prediction of its expansion. Recent outbreaks outside Africa have led to rediscover the human disease but it remains poorly known. The wide spectrum of acute and delayed manifestations with potential unfavorable outcome much complicate the management of suspected cases and prediction of morbidity and mortality during an outbreak. We reviewed literature data on bio-clinical characteristics and treatments of RVF human illness. We identified gaps in the field and provided a practical algorithm to assist clinicians in the cases assessment, determination of setting of care and prolonged follow-up.

Surgical treatment of presbyopia with central presbyopic keratomileusis: One-year results.

PURPOSE: To assess the effectiveness, refractive outcomes, and quality of vision of central presbyopic laser in situ keratomileusis (LASIK) performed with the Custom Q algorithm (Wavelight EX500). SETTING: Ophthalmology Department, Hôpital de la Timone, Marseille, France. DESIGN: Prospective cohort study. METHODS: This study was performed between February 2013 and January 2015. Patients with hyperopia were treated with central presbyopic LASIK. Distance, near, and intermediate visual acuities; objective and subjective refractions; Q factor; keratometry (K); corneal aberrations, and a quality-of-vision questionnaire were evaluated preoperatively and postoperatively. The dominant eye was treated with standard LASIK for distance vision and the nondominant eye for near vision using a Q factor modulation. RESULTS: The study comprised 138 eyes of 28 men and 41 women. The median age was 53.84 years ± 4.2 (SD). One year after surgery, the mean binocular uncorrected distance visual acuity was -0.04 ± 0.05 logMAR (20/20), the mean binocular uncorrected near visual acuity was 0.10 ± 0.08 logMAR (Jaeger 2), and the mean binocular uncorrected intermediate visual acuity was -0.13 ± 0.14 logMAR (20/20). The mean K in nondominant eyes was statistically higher than the mean K in dominant eyes (43.93 ± 1.77 diopters [D] versus 45.85 ± 1.47 D) (P = .002). More than 95% of patients were satisfied 3 months after surgery, and at 6 months, 100% said they would recommend the surgery. CONCLUSION: Central presbyopic LASIK with corneal asphericity modulation using the monovision correction algorithm was effective and safe for presbyopia treatment. FINANCIAL DISCLOSURE: None of the authors has a financial or proprietary interest in any material or method mentioned.