Detalhe da pesquisa
1.
AWZ1066S, a highly specific anti-Wolbachia drug candidate for a short-course treatment of filariasis.
Proc Natl Acad Sci U S A
; 116(4): 1414-1419, 2019 01 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-30617067
2.
Dose prediction for repurposing nitazoxanide in SARS-CoV-2 treatment or chemoprophylaxis.
Br J Clin Pharmacol
; 87(4): 2078-2088, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33085781
3.
Design, synthesis and modelling of photoreactive chemical probes for investigating target engagement of plasmepsin IX and X in Plasmodium falciparum.
RSC Chem Biol
; 5(1): 19-29, 2024 Jan 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-38179191
4.
Identification of 2-Aryl-Quinolone Inhibitors of Cytochrome bd and Chemical Validation of Combination Strategies for Respiratory Inhibitors against Mycobacterium tuberculosis.
ACS Infect Dis
; 9(2): 221-238, 2023 02 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36606559
5.
Targeting the Ubiquinol-Reduction (Qi) Site of the Mitochondrial Cytochrome bc1 Complex for the Development of Next Generation Quinolone Antimalarials.
Biology (Basel)
; 11(8)2022 Jul 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-35892964
6.
Anti-Wolbachia drugs for filariasis.
Trends Parasitol
; 37(12): 1068-1081, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34229954
7.
Development of Pyrazolopyrimidine Anti-Wolbachia Agents for the Treatment of Filariasis.
ACS Med Chem Lett
; 12(9): 1421-1426, 2021 Sep 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34527179
8.
A novel fluorescent probe for the detection of AmpC beta-lactamase and the application in screening beta-lactamase inhibitors.
Spectrochim Acta A Mol Biomol Spectrosc
; 234: 118257, 2020 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32208355
9.
Industrial scale high-throughput screening delivers multiple fast acting macrofilaricides.
Nat Commun
; 10(1): 11, 2019 01 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30602718
10.
The biological evaluation of fusidic acid and its hydrogenation derivative as antimicrobial and anti-inflammatory agents.
Infect Drug Resist
; 11: 1945-1957, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-30498366
11.
Rational Design, Synthesis, and Biological Evaluation of Heterocyclic Quinolones Targeting the Respiratory Chain of Mycobacterium tuberculosis.
J Med Chem
; 60(9): 3703-3726, 2017 05 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-28304162
12.
A tetraoxane-based antimalarial drug candidate that overcomes PfK13-C580Y dependent artemisinin resistance.
Nat Commun
; 8: 15159, 2017 05 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-28537265
13.
Antimalarial Chemotherapy: Natural Product Inspired Development of Preclinical and Clinical Candidates with Diverse Mechanisms of Action.
J Med Chem
; 59(12): 5587-603, 2016 06 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-26791529
14.
Identification, design and biological evaluation of bisaryl quinolones targeting Plasmodium falciparum type II NADH:quinone oxidoreductase (PfNDH2).
J Med Chem
; 55(5): 1831-43, 2012 Mar 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-22364416
15.
Identification, design and biological evaluation of heterocyclic quinolones targeting Plasmodium falciparum type II NADH:quinone oxidoreductase (PfNDH2).
J Med Chem
; 55(5): 1844-57, 2012 Mar 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-22364417