Detalhe da pesquisa
1.
Protein Kinase Cϵ (PKCϵ) Promotes Synaptogenesis through Membrane Accumulation of the Postsynaptic Density Protein PSD-95.
J Biol Chem
; 291(32): 16462-76, 2016 08 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-27330081
2.
Rescue of Synaptic Phenotypes and Spatial Memory in Young Fragile X Mice.
J Pharmacol Exp Ther
; 357(2): 300-10, 2016 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-26941170
3.
Bryostatin-1 restores hippocampal synapses and spatial learning and memory in adult fragile x mice.
J Pharmacol Exp Ther
; 349(3): 393-401, 2014 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-24659806
4.
Bryostatin improves survival and reduces ischemic brain injury in aged rats after acute ischemic stroke.
Stroke
; 44(12): 3490-7, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-24172582
5.
PKC activation during training restores mushroom spine synapses and memory in the aged rat.
Neurobiol Dis
; 55: 44-62, 2013 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-23545166
6.
PKCε activator protects hippocampal microvascular disruption and memory defect in 3×Tg-Alzheimer's disease mice with cerebral microinfarcts.
Front Aging Neurosci
; 15: 1272361, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-38187357
7.
Association of Apolipoprotein E4-related Microvascular Disease in the Alzheimer's Disease Hippocampal CA1 Stratum Radiatum.
Neuroscience
; 526: 204-222, 2023 08 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-37385335
8.
PKC ε activation prevents synaptic loss, Aß elevation, and cognitive deficits in Alzheimer's disease transgenic mice.
J Neurosci
; 31(2): 630-43, 2011 Jan 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-21228172
9.
Postischemic PKC activation rescues retrograde and anterograde long-term memory.
Proc Natl Acad Sci U S A
; 106(34): 14676-80, 2009 Aug 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-19667190
10.
PKCε Activation Restores Loss of PKCε, Manganese Superoxide Dismutase, Vascular Endothelial Growth Factor, and Microvessels in Aged and Alzheimer's Disease Hippocampus.
Front Aging Neurosci
; 14: 836634, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35299945
11.
HIV Promotes Neurocognitive Impairment by Damaging the Hippocampal Microvessels.
Mol Neurobiol
; 59(8): 4966-4986, 2022 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-35665894
12.
PKC activator therapeutic for mild traumatic brain injury in mice.
Neurobiol Dis
; 41(2): 329-37, 2011 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-20951803
13.
Poststroke neuronal rescue and synaptogenesis mediated in vivo by protein kinase C in adult brains.
Proc Natl Acad Sci U S A
; 105(36): 13620-5, 2008 Sep 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-18768786
14.
A structural basis for enhancement of long-term associative memory in single dendritic spines regulated by PKC.
Proc Natl Acad Sci U S A
; 104(49): 19571-6, 2007 Dec 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-18073185
15.
Insulin, PKC signaling pathways and synaptic remodeling during memory storage and neuronal repair.
Eur J Pharmacol
; 585(1): 76-87, 2008 May 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-18402935
16.
Hippocampal microvasculature changes in association with oxidative stress in Alzheimer's disease.
Free Radic Biol Med
; 120: 192-203, 2018 05 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-29572097
17.
Loss in PKC Epsilon Causes Downregulation of MnSOD and BDNF Expression in Neurons of Alzheimer's Disease Hippocampus.
J Alzheimers Dis
; 63(3): 1173-1189, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29710707
18.
Effects of chronic bryostatin-1 on treatment-resistant depression in rats.
Eur J Pharmacol
; 807: 71-74, 2017 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28472666
19.
Strong calcium entry activates mitochondrial superoxide generation, upregulating kinase signaling in hippocampal neurons.
J Neurosci
; 24(48): 10878-87, 2004 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-15574738
20.
Correlated calcium uptake and release by mitochondria and endoplasmic reticulum of CA3 hippocampal dendrites after afferent synaptic stimulation.
J Neurosci
; 22(24): 10653-61, 2002 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-12486158