Detalhe da pesquisa
1.
Functional analysis and clinical classification of 462 germline BRCA2 missense variants affecting the DNA binding domain.
Am J Hum Genet
; 111(3): 584-593, 2024 Mar 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-38417439
2.
Strong functional data for pathogenicity or neutrality classify BRCA2 DNA-binding-domain variants of uncertain significance.
Am J Hum Genet
; 108(3): 458-468, 2021 03 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33609447
3.
A Population-Based Study of Genes Previously Implicated in Breast Cancer.
N Engl J Med
; 384(5): 440-451, 2021 02 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33471974
4.
Gene regulatory network inference based on a nonhomogeneous dynamic Bayesian network model with an improved Markov Monte Carlo sampling.
BMC Bioinformatics
; 24(1): 264, 2023 Jun 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-37355560
5.
Salicylates enhance CRM1 inhibitor antitumor activity by induction of S-phase arrest and impairment of DNA-damage repair.
Blood
; 137(4): 513-523, 2021 01 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-33507295
6.
Assessment of the Clinical Relevance of BRCA2 Missense Variants by Functional and Computational Approaches.
Am J Hum Genet
; 102(2): 233-248, 2018 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29394989
7.
Covalent Organic Framework-Titanium Oxide Nanocomposite for Enhanced Sonodynamic Therapy.
Bioconjug Chem
; 32(4): 661-666, 2021 04 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-33710853
8.
Mutation prevalence tables for hereditary cancer derived from multigene panel testing.
Hum Mutat
; 41(8): e1-e6, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32442341
9.
Knockout of sulfatase 2 is associated with decreased steatohepatitis and fibrosis in a mouse model of nonalcoholic fatty liver disease.
Am J Physiol Gastrointest Liver Physiol
; 319(3): G333-G344, 2020 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32683952
10.
Classification of variants of uncertain significance in BRCA1 and BRCA2 using personal and family history of cancer from individuals in a large hereditary cancer multigene panel testing cohort.
Genet Med
; 22(4): 701-708, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-31853058
11.
Functional characterization of 84 PALB2 variants of uncertain significance.
Genet Med
; 22(3): 622-632, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31636395
12.
A clinical guide to hereditary cancer panel testing: evaluation of gene-specific cancer associations and sensitivity of genetic testing criteria in a cohort of 165,000 high-risk patients.
Genet Med
; 22(2): 407-415, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31406321
13.
Copper-Doped Nanoscale Covalent Organic Polymer for Augmented Photo/Chemodynamic Synergistic Therapy and Immunotherapy.
Bioconjug Chem
; 31(6): 1661-1670, 2020 06 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-32393025
14.
Evaluation of ACMG-Guideline-Based Variant Classification of Cancer Susceptibility and Non-Cancer-Associated Genes in Families Affected by Breast Cancer.
Am J Hum Genet
; 98(5): 801-817, 2016 May 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-27153395
15.
One-Pot Synthesis of DOX@Covalent Organic Framework with Enhanced Chemotherapeutic Efficacy.
Chemistry
; 25(17): 4315-4319, 2019 Mar 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-30735271
16.
Cancer susceptibility gene mutations in type I and II endometrial cancer.
Gynecol Oncol
; 152(1): 20-25, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30612635
17.
Long Noncoding RNA HOTTIP Promotes Mouse Hepatic Stellate Cell Activation via Downregulating miR-148a.
Cell Physiol Biochem
; 51(6): 2814-2828, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-30562760
18.
Association Between Inherited Germline Mutations in Cancer Predisposition Genes and Risk of Pancreatic Cancer.
JAMA
; 319(23): 2401-2409, 2018 06 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-29922827
19.
Circulating tumor cells are associated with poor overall survival in patients with cholangiocarcinoma.
Hepatology
; 63(1): 148-58, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-26096702
20.
Frequency of mutations in a large series of clinically ascertained ovarian cancer cases tested on multi-gene panels compared to reference controls.
Gynecol Oncol
; 147(2): 375-380, 2017 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-28888541