Detalhe da pesquisa
1.
Accurate de novo design of membrane-traversing macrocycles.
Cell
; 185(19): 3520-3532.e26, 2022 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36041435
2.
Scanning mutagenesis identifies residues that improve the long-term stability and insecticidal activity of cyclotide kalata B1.
J Biol Chem
; 300(3): 105682, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38272233
3.
The complexed crystal structure of dihydropyrimidinase reveals a potential interactive link with the neurotransmitter γ-aminobutyric acid (GABA).
Biochem Biophys Res Commun
; 692: 149351, 2024 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38056157
4.
Season of death, pathogen persistence and wildlife behaviour alter number of anthrax secondary infections from environmental reservoirs.
Proc Biol Sci
; 291(2016): 20232568, 2024 Feb 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-38320613
5.
Computational Design of α-Conotoxins to Target Specific Nicotinic Acetylcholine Receptor Subtypes.
Chemistry
; 30(7): e202302909, 2024 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37910861
6.
Isolation and Characterization of Insecticidal Cyclotides from Viola communis.
J Nat Prod
; 2024 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38747744
7.
Mutagenesis of bracelet cyclotide hyen D reveals functionally and structurally critical residues for membrane binding and cytotoxicity.
J Biol Chem
; 298(4): 101822, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35283188
8.
The acyclotide ribe 31 from Rinorea bengalensis has selective cytotoxicity and potent insecticidal properties in Drosophila.
J Biol Chem
; 298(10): 102413, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36007611
9.
Antiviral therapy reduces hepatocellular carcinoma through suppressing hepatitis B virus replication may improve ER stress, mitochondrial and metabolic dysfunctions and decrease p62 in hybridized mice with single HBV transgene and miR-122.
J Med Virol
; 95(12): e29325, 2023 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-38108211
10.
Nematicidal Activity of Cyclotides: Toxicity Against Caenorhabditis elegans.
J Nat Prod
; 86(5): 1222-1229, 2023 05 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-37099442
11.
Crystal Structure of DNA Replication Protein SsbA Complexed with the Anticancer Drug 5-Fluorouracil.
Int J Mol Sci
; 24(19)2023 Oct 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-37834349
12.
Crystal Structure of Allantoinase from Escherichia coli BL21: A Molecular Insight into a Role of the Active Site Loops in Catalysis
Molecules
; 28(2)2023 Jan 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-36677881
13.
Improving Stability Enhances In Vivo Efficacy of a PCSK9 Inhibitory Peptide.
J Am Chem Soc
; 144(42): 19485-19498, 2022 10 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-36222719
14.
ÉO-Conotoxin GeXIVA isomers modulate N-type calcium (CaV 2.2) channels and inwardly-rectifying potassium (GIRK) channels via GABAB receptor activation.
J Neurochem
; 160(2): 154-171, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34738241
15.
Genetic and Biochemical Characterization of Halogenation and Drug Transportation Genes Encoded in the Albofungin Biosynthetic Gene Cluster.
Appl Environ Microbiol
; 88(17): e0080622, 2022 09 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-36000868
16.
Clinical Implications of HBV PreS/S Mutations and the Effects of PreS2 Deletion on Mitochondria, Liver Fibrosis, and Cancer Development.
Hepatology
; 74(2): 641-655, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33675094
17.
The r-X1 deletion induces terminal deficiencies in the maize B chromosome.
Chromosome Res
; 29(3-4): 351-360, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34480269
18.
Whole genome sequencing identifies genetic variants associated with co-trimoxazole hypersensitivity in Asians.
J Allergy Clin Immunol
; 147(4): 1402-1412, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32791162
19.
Crystal Structure of an SSB Protein from Salmonella enterica and Its Inhibition by Flavanonol Taxifolin.
Int J Mol Sci
; 23(8)2022 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35457218
20.
Prolactin and endocrine therapy resistance in breast cancer: The next potential hope for breast cancer treatment.
J Cell Mol Med
; 25(22): 10327-10348, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34651424