Detalhe da pesquisa
1.
Tuning the Baird aromatic triplet-state energy of cyclooctatetraene to maximize the self-healing mechanism in organic fluorophores.
Proc Natl Acad Sci U S A
; 117(39): 24305-24315, 2020 09 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-32913060
2.
Development of substituted benzimidazoles as inhibitors of human aldehyde dehydrogenase 1A isoenzymes.
Chem Biol Interact
; 391: 110910, 2024 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38364885
3.
Development of 2,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one inhibitors of aldehyde dehydrogenase 1A (ALDH1A) as potential adjuncts to ovarian cancer chemotherapy.
Eur J Med Chem
; 211: 113060, 2021 Feb 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33341649
4.
The chemotherapeutic CX-5461 primarily targets TOP2B and exhibits selective activity in high-risk neuroblastoma.
Nat Commun
; 12(1): 6468, 2021 11 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34753908
5.
Design and Application of a High-Throughput, High-Content Screening System for Natural Product Inhibitors of the Human Parasite Trichomonas vaginalis.
ACS Infect Dis
; 5(8): 1456-1470, 2019 08 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31265248
6.
A Pan-ALDH1A Inhibitor Induces Necroptosis in Ovarian Cancer Stem-like Cells.
Cell Rep
; 26(11): 3061-3075.e6, 2019 03 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30865894
7.
Structure-Based Optimization of a Novel Class of Aldehyde Dehydrogenase 1A (ALDH1A) Subfamily-Selective Inhibitors as Potential Adjuncts to Ovarian Cancer Chemotherapy.
J Med Chem
; 61(19): 8754-8773, 2018 10 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30221940