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Developing facile approaches for preparing efficient electrocatalysts is of significance to promote sustainable energy technologies. Here, we report a facile iron-oxidizing bacteria corrosion approach to construct a composite electrocatalyst of nickeliron oxyhydroxides combined with iron oxides. The obtained electrocatalyst shows improved electrocatalytic activity and stability for oxygen evolution, with an overpotential of â¼230 mV to afford the current density of 10 mA cm−2. The incorporation of iron oxides produced by iron-oxidizing bacteria corrosion optimizes the electronic structure of nickeliron oxyhydroxide electrodes, which accounts for the decreased free energy of oxygenate generation and the improvement of OER activity. This work demonstrates a natural bacterial corrosion approach for the facile preparation of efficient electrodes for water oxidation, which may provide interesting insights in the multidisciplinary integration of innovative nanomaterials and emerging energy technologies.
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Níquel , Oxigênio , Microbiologia da Água , Corrosão , Compostos Férricos , Ferro , ÁguaRESUMO
Various acoustic materials are developed to resolve noise pollution problem in many industries. Especially, materials with porous structure are broadly used to absorb sound energy in civil construction and transportation area. Polyurethane (PU) porous materials possess excellent damping properties, good toughness, and well-developed pore structures, which have a broad application prospect in sound absorption field. This work aims to summarize the recent progress of fabrication and structure for PU porous materials in sound absorption application. The sound absorption mechanisms of porous materials are introduced. Different kinds of structure for typical PU porous materials in sound absorption application are covered and highlighted, which include PU foam, modified PU porous materials, aerogel, templated PU, and special PU porous materials. Finally, the development direction and existing problems of PU material in sound absorption application are briefly prospected. It can be expected that porous PU with high sound absorption coefficient can be obtained by using some facile methods. The design and accurate regulation of porous structures or construction of multilayer sound absorption structure is favorably recommended to fulfill the high demand of industrial and commercial applications in the future work.
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Poliuretanos , Poliuretanos/química , Porosidade , SomRESUMO
Transition-metal-based oxygen evolution reaction (OER) catalysts have attracted widespread attention due to their inexpensive prices, unique layered structures, and rich active sites. Currently, designing low-cost, sustainable, and simple synthesis methods is essential for the application of transition-metal-based catalysts. Here, magnetic field (MF)-assisted chemical corrosion, as a novel technology, is adopted to construct superior OER electrocatalysts. The produced Ni(Fe)(OH)2-Fe2O3 electrode exhibits an overpotential of 272 mV at a current density of 100 mA cm-2, presenting a 64 mV reduction compared to the electrode without an MF. The experimental results indicate that an MF can induce the directional growth of Fe2O3 rods and reduce their accumulation. In addition, an external MF is beneficial for the lattice dislocation of the obtained catalysts, which can increase the surface free energy, thus reducing the activation energy and accelerating the electrochemical reaction kinetics. This work effectively combines a magnetic field with chemical corrosion and electrochemical energy, which offers a novel strategy for the large-scale development of environmentally friendly and superior electrocatalysts.
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BACKGROUND: To better understand the efficacy and safety of Bifidobacterium quadruple viable tablets in the treatment of helicobacter pylori (H. pylori)-infected peptic ulcer or gastritis patients. METHODS: A systematic review of the studies published to June 2022 was performed in English database PubMed, Embase, Chinese database CNKI, Wanfang. There were 17 studies were included in this systematic review and meta-analysis. The outcomes measured included H. pylori eradication rate, changes in clinical symptoms of epigastric pain scores, and the incidence of adverse reactions. RESULTS: The results of the fixed effect model showed that the eradication rate of H. pylori in the combination of Bifidobacterium quadruple viable bacteria tablets combined with bismuth-containing conventional quadruple therapy was greater than that of bismuth-containing conventional quadruple therapy, and the difference was statistically significant (OR = 3.73, 95%CI (2.79,5.00), Z = 2.78, P < 0.001; I2 = 0.0%, P > 0.999). The results of random effects model showed that the epigastric pain score of Bifidobacterium quadruple viable bacteria tablets combined with bismuth-containing conventional quadruple therapy was lower than that of bismuth-containing conventional quadruple therapy, and the difference was statistically significant (WMD=-0.70, 95%CI (-1.06,-0.34), Z = 3.82, P < 0.001; I2 = 96.7%, P < 0.001). The results of random effects model showed that the acid reflux score of Bifidobacterium quadruple viable bacteria tablets combined with bismuth-containing conventional quadruple therapy was lower than that of bismuth-containing conventional quadruple therapy, and the difference was statistically significant (WMD=-0.98, 95%CI (-1.70,-0.26), Z = 2.66, P < 0.001; I2 = 99.7%, P < 0.001). CONCLUSIONS: The eradication rate of H. pylori by Bifidobacterium quadruple viable bacteria tablets combined with bismuth-containing quadruple therapy is better than that of bismuth-containing quadruple therapy. The improvement of clinical symptoms of patients is better than that of bismuth-containing quadruple therapy, and the incidence of adverse reactions is lower than that of bismuth-containing quadruple therapy. Bifidobacterium quadruple viable bacteria tablet combined with bismuth-containing quadruple therapy was effective and safe. It provides a new way to treat patients with H. pylori.
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Gastrite , Helicobacter pylori , Úlcera Péptica , Humanos , Bismuto , Úlcera Péptica/tratamento farmacológico , Dor Abdominal , Bifidobacterium , Gastrite/tratamento farmacológico , ComprimidosRESUMO
PURPOSE: After the COVID-19 pandemic, many challenges arose regarding the impact of this disease on people with ulcerative colitis. The aims of this study were to estimate the prevalence, severity, and death consequences of COVID-19 in patients with ulcerative colitis using a systematic review and meta-analysis. METHODS: This study was conducted using a systematic review and meta-analysis method in the field of prevalence, severity, and clinical consequences of COVID-19 in people with ulcerative colitis worldwide. The search was conducted in international scientific databases, such as Web of Science, PubMed, Scopus, Cochrane Library, and Google Scholar, from the beginning of 2020 to October 2023. The quality of the eligible studies was assessed using the Strobe and Newcastle Ottawa checklists. The data were analyzed using a fixed-effects model in the meta-analysis. Subgroup analysis and meta-regression were performed using STATA version 17. RESULTS: Nineteen studies with a sample size of 224,520 patients were included in this meta-analysis. The results showed that, in COVID-19 patients with ulcerative colitis, the prevalence of hospitalization, death, COVID-19 severity, and mortality rate in severe patients was 54% (95% CI, 27-80%), 10% (95% CI, 4-16%), 20% (95% CI, 8-34%), 63% (95% CI, 46-80%), respectively. In comparison with the general population, the odds ratio (OR) of hospitalization in patients due to COVID-19 was OR = 1.28 (95% CI, 1.19-1.38, P < 0.001), and the chance of severe COVID-19 was OR = 1.30 (95% CI, 1.22-1.53, P < 0.001). CONCLUSION: The probability of contracting the severe type of COVID-19 and hospitalization in patients with ulcerative colitis was higher than in the general population.
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COVID-19 , Colite Ulcerativa , Humanos , COVID-19/epidemiologia , Colite Ulcerativa/complicações , Colite Ulcerativa/epidemiologia , Pandemias , Bases de Dados Factuais , HospitalizaçãoRESUMO
High-performance polypropylene (PP) foam is a vital polymer product in industrial areas. However, the poor melt strength of ordinary PP homopolymer limits its foaming molding. In this work, high melt strength polypropylene (HMSPP) is prepared by using styrene (St) and tripropylene glycol diacrylate (TPGDA) as comonomers, and then PP foams are prepared by mold foaming method. The results show that adding St in the grafting process of TPGDA will obviously improve the melt strength of the PP matrix, and its melt strength (28â¯184 Pa.s) is 7.4 times higher than that of pure PP. HMSPP foam has more regular and uniform cells and higher cell density, which significantly improves the sound and thermal insulation properties of PP foam. Compared with pure PP foam, the average sound transmission loss (52.9 dB) of HMSPP foam with a low foaming ratio increased by 64%, and the thermal conductivity (0.0867 W mK-1 ) decreased by 46%. Therefore, the obtained HMSPP foam can be used in sound insulation or thermal insulation area. This work provides an available route for the high-performance utilization of PP foam.
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Acrilatos , Polipropilenos , Polímeros , Propilenoglicóis , EstirenoRESUMO
Large-scale production of green and pollution-free materials is crucial for deploying sustainable clean energy. Currently, the fabrication of traditional energy materials involves complex technological conditions and high costs, which significantly limits their broad application in the industry. Microorganisms involved in energy production have the advantages of inexpensive production and safe process and can minimize the problem of chemical reagents in environmental pollution. This paper reviews the mechanisms of electron transport, redox, metabolism, structure, and composition of electroactive microorganisms in synthesizing energy materials. It then discusses and summarizes the applications of microbial energy materials in electrocatalytic systems, sensors, and power generation devices. Lastly, the research progress and existing challenges for electroactive microorganisms in the energy and environment sectors described herein provide a theoretical basis for exploring the future application of electroactive microorganisms in energy materials.
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Tecnologia , Transporte de Elétrons , Fenômenos FísicosRESUMO
Currently, aqueous zinc-ion batteries, with large reserves of zinc metal and maturity of production, are a promising alternative to sustainable energy storage. Nevertheless, aqueous solution has poor frost resistance and is prone to side reactions. In addition, zinc dendrites also limit the performance of zinc-ion batteries. Biomass, with complex molecular structure and abundant functional groups, makes it have great application prospects. In this review, the research progress of biomass and its derived materials used in zinc-ion batteries are reviewed. The different regulation strategies and characteristics of biomass used in zinc-ion battery electrodes, electrolyte separators and binders are demonstrated. The regulation mechanism is analyzed. At the end, the development prospect and challenges of biomass in energy materials application are proposed.
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BACKGROUND: Faecal microbiota transplantation (FMT) is an effective therapy for recurrent Clostridium difficile infections and chronic gastrointestional infections. However, the risks of FMT and the selection process of suitable donors remain insufficiently characterized. The eligibility rate for screening, underlying microbial basis, and core ethical issues of stool donors for FMT are yet to be elucidated in China. RESULTS: The potential stool donors were screened from December 2017 to December 2019 with the help of an online survey, clinical assessments, and stool and blood testing. Bioinformatics analyses were performed, and the composition and stability of gut microbiota in stool obtained from eligible donors were dynamically observed using metagenomics. Meanwhile, we build a donor microbial evaluation index (DoMEI) for stool donor screening. In the screening process, we also focused on ethical principles and requirements. Of the 2071 participants, 66 donors were selected via the screening process (3.19% success rate). Although there were significant differences in gut microbiota among donors, we found that the changes in the gut microbiota of the same donor were typically more stable than those between donors over time. CONCLUSIONS: DoMEI provides a potential reference index for regular stool donor re-evaluation. In this retrospective study, we summarised the donor recruitment and screening procedure ensuring the safety and tolerability for FMT in China. Based on the latest advances in this field, we carried out rigorous recommendation and method which can assist stool bank and clinicians to screen eligible stool donor for FMT.
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Seleção do Doador/métodos , Transplante de Microbiota Fecal/métodos , Fezes/microbiologia , Microbioma Gastrointestinal/genética , Metagenômica/métodos , Doadores de Tecidos , Adolescente , Adulto , China , Infecções por Clostridium/terapia , Biologia Computacional/métodos , Feminino , Humanos , Masculino , Estudos Retrospectivos , Adulto JovemRESUMO
GOAL: To evaluate the efficacy of low-dose (3.5 mg/kg) infliximab for induction and maintenance treatment in Chinese patients with ulcerative colitis. BACKGROUND: Treatment with 4 to 5 mg/kg of infliximab also proved to be effective in treating moderate to severe ulcerative colitis. At present there is no relevant study on the effectiveness of infliximab doses lower than 4 mg/kg in patients with ulcerative colitis. STUDY: A prospective, randomized, double-blind, placebo-controlled, and single-centered study was designed. A total of 123 patients (from 17 provinces of China) with moderate to severe active ulcerative colitis despite treatment with concurrent drugs received placebo or low-dose (3.5 mg/kg) or standard-dose (5 mg/kg) infliximab intravenously at weeks 0, 2, and 6 and then every 8 weeks through week 22. Patients were followed up for 30 weeks. RESULTS: Overall, 73% and 78% of patients who received low-dose (3.5 mg/kg) and standard-dose (5 mg/kg) infliximab, respectively, had clinical responses at week 8, as compared with 37% of patients who received placebo (P<0.01 for both comparisons with placebo). The number of patients who received low-dose (3.5 mg/kg) or standard-dose (5 mg/kg) infliximab with a clinical response at week 30 (63% and 66%, respectively) was more than the patients who received placebo (27%, P<0.01 for both comparisons). CONCLUSIONS: Chinese patients with moderate to severe active ulcerative colitis treated with low-dose (3.5 mg/kg) or standard-dose (5 mg/kg) infliximab at weeks 0, 2, and 6 and every 8 weeks thereafter were more likely to have a clinical response at weeks 8 and 30 than those who received placebo.
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Colite Ulcerativa/tratamento farmacológico , Fármacos Gastrointestinais/administração & dosagem , Quimioterapia de Indução , Infliximab/administração & dosagem , Quimioterapia de Manutenção , Adulto , China , Relação Dose-Resposta a Droga , Método Duplo-Cego , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Prospectivos , Resultado do TratamentoRESUMO
BACKGROUND: The relapse rate of ulcerative colitis (UC) is high. The efficacy of combined diosmectite and mesalazine treatment for active mild-to-moderate UC was investigated. MATERIAL/METHODS: A total of 120 patients with UC were enrolled in this randomized, single-blind, placebo-controlled study. Sixty patients were assigned to the Diosmectite group (diosmectite and mesalazine) and 60 were assigned to Placebo group (placebo and mesalazine). In the induction phase, the primary end point was the clinical remission rate at 8 weeks; secondary end points were clinical response, endothelial mucosal healing, Mayo score, erythrocyte sedimentation rate, C-reactive protein levels, and defecation frequency. In the maintenance phase, the primary end point was clinical remission at 52 weeks; secondary end points were clinical response, endothelial mucosal healing, Mayo score, erythrocyte sedimentation rate, and defecation frequency. RESULTS: At 8 weeks, the Diosmectite group had a significantly higher clinical remission rate (68.3% vs. 50%) and mucosal healing rate (66.7% vs. 48.3%) compared with the Placebo group. There were no significant differences in clinical response rates, Mayo score, erythrocyte sedimentation rate, C-reactive protein, or defecation frequency. At 52 weeks, the Diosmectite group had a significantly higher clinical remission rate (61.7% vs. 40%) and mucosal healing rate (60% vs. 38.3%) compared with the Placebo group. Defecation frequency was lower, but this was not significant. CONCLUSIONS: Combined diosmectite and mesalazine treatment successfully induced and maintained the treatment of active mild-to-moderate UC as indicated by higher rates of clinical remission and mucosal healing.
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Colite Ulcerativa/tratamento farmacológico , Mesalamina/administração & dosagem , Silicatos/administração & dosagem , Adolescente , Adulto , Idoso , Sedimentação Sanguínea/efeitos dos fármacos , Proteína C-Reativa/química , Defecação/efeitos dos fármacos , Quimioterapia Combinada/métodos , Feminino , Humanos , Mucosa Intestinal/efeitos dos fármacos , Masculino , Pessoa de Meia-Idade , Estudos Prospectivos , Indução de Remissão , Índice de Gravidade de Doença , Método Simples-Cego , Resultado do Tratamento , Adulto JovemRESUMO
Developing highly efficient and sustainable hydrogen evolution reaction (HER) electrocatalysts is important for the practical application of emerging energy technologies. The spherical structure and phosphorus-rich properties of Chlorella can facilitate the construction of comparable transition metal phosphide electrocatalysts. Here, a microorganism template strategy is proposed to construct a cobalt-phosphide-graphene hybrid. Chlorella can absorb metal ions, and the generated rough spherical nanoparticles are uniformly distributed around the reduced graphene oxide nanosheets. This designed catalyst has comparable HER performance in acidic electrolytes and needs an overpotential of only 153 mV at a current density of 10 mA cm-2. The experimental and density functional theory results imply that the charge redistribution between Co2P and pyrrole-N is the key factor in enhancing the HER activity. The induced electron aggregation at the N and P sites can serve as a key active site for absorbing the adsorbed hydrogen atom intermediate to accelerate the HER process, contributing to the active sites of Co2P- and pyrrole-N-doped carbon with 0 eV hydrogen adsorption free energy. This work provides a broad idea for synthesizing advanced catalysts by a biological template approach, facilitating the innovative integration of biology and emerging electrochemical energy technologies.
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A Cu-mediated trifluoromethylation of benzyl, allyl and propargyl methanesulfonates with TMSCF3 was developed for the first time. This method offers a convenient and economical approach to various trifluoroethyl-containing compounds.
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The prospect of ionic conductive hydrogels in multifunctional sensors has generated widespread scientific interest. The new generation of flexible materials should be combined with superior mechanical properties, high conductivity, transparency, sensitivity, good self-restoring fatigue properties, and other multifunctional characteristics, while the current materials are difficult to meet these requirements. Herein, we prepared poly(acrylamide-acrylic acid) (P(AM-AA))/gelatin/glycerol-Al3+ (PG1G2A) ionic conducting hydrogel by one-pot polymerization under UV light. The prepared PG1G2A ionic conductive hydrogel had high tensile strength (539.18 kPa), excellent tensile property (1412.96%), good fast self-recovery and fatigue resistance, high transparency (>80%), excellent moisturizing, and antifreezing/drying properties. In addition, the ionic conductive hydrogel-based strain sensor can respond to mechanical stimulation and generate accurate, stable, and recyclable electrical signals, with excellent sensitivity (GF 5.81). In addition, the PG1G2A hydrogel could be used as flexible wearable devices for monitoring multiple strain and subtle movements of different body parts at different temperatures. Interestingly, the PG1G2A hydrogel capacitive pen embedded in the mold can be used to write and draw on the screen of a phone or tablet. This new multifunctional ionic conducting hydrogel shows broad application prospects in E-skin, motion monitoring, and human-computer interaction in extreme environments.
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Rubber is widely recognized as an important material, whose irreplaceable applications range from damping materials to tires. Generally, rubber is vulnerable to oxidative degradation, leading to a deterioration in the material's performance. Therefore, antioxidants are often added to extend the service life of rubber. In this study, crude lignin-based carbon dots (CLCDs) were prepared by a simple hydrothermal treatment of lignin with H2O2 and triethylenetetramine. The thus prepared CLCDs exhibit excellent radical scavenging capability, and were incorporated into natural rubber with vinyl pyridine-styrene-butadiene terpolymer (VPR) as coupling agent. The results revealed that CLCDs could endow NR with excellent antioxidative performance. Interestingly, CLCDs even show superior antioxidant effect towards rubber compared to purified lignin-based carbon dots (PLCDs). This work provides a unique source of inspiration for the preparation of low-cost, highly effective CLCDs from plant biomass waste, most of lignin being used to produce steam and energy, with excellent antioxidant capability for rubber, which is beneficial for a green and sustainable world.
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Lignina , Borracha , Carbono , Antioxidantes/farmacologia , Peróxido de HidrogênioRESUMO
No prediction rule is currently available for advanced colorectal neoplasms, defined as invasive cancer, an adenoma of 10 mm or more, a villous adenoma, or an adenoma with high-grade dysplasia, in average-risk Chinese. In this study between 2006 and 2008, a total of 7,541 average-risk Chinese persons aged 40 years or older who had complete colonoscopy were included. The derivation and validation cohorts consisted of 5,229 and 2,312 persons, respectively. A prediction rule was developed from a logistic regression model and then internally and externally validated. The prediction rule comprised 8 variables (age, sex, smoking, diabetes mellitus, green vegetables, pickled food, fried food, and white meat), with scores ranging from 0 to 14. Among the participants with low-risk (≤3) or high-risk (>3) scores in the validation cohort, the risks of advanced neoplasms were 2.6% and 10.0% (P < 0.001), respectively. If colonoscopy was used only for persons with high risk, 80.3% of persons with advanced neoplasms would be detected while the number of colonoscopies would be reduced by 49.2%. The prediction rule had good discrimination (area under the receiver operating characteristic curve = 0.74, 95% confidence interval: 0.70, 0.78) and calibration (P = 0.77) and, thus, provides accurate risk stratification for advanced neoplasms in average-risk Chinese.
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Adenoma , Colonoscopia , Neoplasias Colorretais , Técnicas de Apoio para a Decisão , Detecção Precoce de Câncer , Adenoma/diagnóstico , Adenoma/etiologia , Adulto , Fatores Etários , Idoso , China , Neoplasias Colorretais/diagnóstico , Neoplasias Colorretais/etiologia , Estudos Transversais , Feminino , Humanos , Modelos Logísticos , Masculino , Programas de Rastreamento , Pessoa de Meia-Idade , Curva ROC , Medição de Risco , Fatores Sexuais , Inquéritos e QuestionáriosRESUMO
Trifluoromethylated acetylenes and arenes are widely applicable in the synthesis of pharmaceuticals and agrochemicals. In 2010, our group has reported the copper-mediated oxidative trifluomethylation of terminal alkynes and aryl boronic acids. This method allows a wide range of functional group tolerant trifluoromethylated acetylenes and arenes to be easily prepared. After the preliminary mechanistic studies of the oxidative trifluoromethylation of terminal alkyne, an efficient copper-catalyzed oxidative trifluoromethylation of terminal alkynes and aryl boronic acids has been developed. The catalytic protocol is successfully achieved by adding both the substrate and a portion of CF(3)TMS slowly using a syringe pump to the reaction mixture.
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Alcinos/química , Ácidos Borônicos/química , Cobre/química , Hidrocarbonetos Fluorados/química , Silanos/química , Catálise , Metilação , OxirreduçãoRESUMO
A practical and efficient synthesis of C(3)-trifluoromethanesulfanylated hexahydropyrrolo[2,3-b]indoles 5 from tryptamine derivatives was described. The features of this synthesis included electrophilic activation of C(3) of tryptamine derivatives with "CF(3)S(+)" and cascade ring cyclization by carbamate nucleophile attacking at C(2). Surprisingly, when Lewis acid (BF(3)·OEt(2)) was used as activator instead of proton acid (TsOH·H(2)O) for the electrophilic trifluoromethanesulfanylation of tryptamine derivatives, the uncyclized product 6 was formed preferentially. This sequential trifluoromethanesulfanylation-cyclization protocol was used to synthesize several pyrrolidinoindolinic alkaloid analogues. The cytotoxicity activities of these trifluoromethanesulfanylated alkaloid analogues were evaluated against three cancer cell lines (K562, HeLa, L929).
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Clorofluorcarbonetos de Metano/síntese química , Indóis/síntese química , Pirróis/síntese química , Compostos de Sulfidrila/síntese química , Triptaminas/química , Clorofluorcarbonetos de Metano/química , Ciclização , Indóis/química , Estrutura Molecular , Pirróis/química , Estereoisomerismo , Compostos de Sulfidrila/químicaRESUMO
Background: Intervertebral disc degeneration (IDD) is a major cause of low back pain, but the onset and progression of IDD are unknown. Long non-coding RNA (lncRNA) has been validated to play a critical role in IDD, while an increasing number of studies have linked oxidative stress (OS) to the initiation and progression of IDD. We aim to investigate key lncRNAs in IDD through a comprehensive network of competing endogenous RNA (ceRNA) and to identify possible underlying mechanisms. Methods: We downloaded IDD-related gene expression data from the Gene Expression Omnibus (GEO) database and obtained differentially expressed-lncRNAs (DE-lncRNA), -microRNAs (DE-miRNA), and -messenger RNAs (DE-mRNA) by bioinformatics analysis. The OS-related lncRNA-miRNA-mRNA ceRNA interaction axis was constructed and key lncRNAs were identified based on ceRNA theory. We performed gene ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analyses on mRNAs regulated by lncRNAs in the ceRNA network. Single sample gene set enrichment analysis (ssGSEA) was used to reveal the immune landscape. Expression of key lncRNAs in IDD was assessed by quantitative reverse transcription-polymerase chain reaction (qRT-PCR). Results: In this study, 111 DE-mRNAs, 20 DE-lncRNAs, and 502 DE-miRNAs were identified between IDD patients and controls, and 16 OS-related DE-lncRNAs were also identified. The resulting lncRNA-miRNA-mRNA network consisted of eight OS-related DE-lncRNA nodes, 24 DE-miRNA nodes, 70 DE-mRNA nodes, and 183 edges. Functional enrichment analysis suggested that the ceRNA network may be involved in regulating biological processes related to cytokine secretion, lipid, and angiogenesis. We also identified four key lncRNAs, namely lncRNA GNAS-AS1, lncRNA MIR100HG, lncRNA LINC01359, and lncRNA LUCAT1, which were also found to be significantly associated with immune cells. Conclusion: These results provide novel insights into the potential applications of OS-related lncRNAs in patients with IDD.
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In view of the current trend of capacitor materials, the development of capacitors with high dielectric permittivity and low dielectric loss is of great interest. In this work, the dielectric permittivity of reduced graphene oxide-incorporated styrene-butyl acrylate (rGO@SBA) composite microspheres synthesized by mini-emulsion polymerization was significantly improved. rGO with 2 wt% content gave a dielectric permittivity of 11 356 (at 1 KHz), which was 1925 times higher than that of pure SBA (5.9). SEM and TEM were conducted to observe the morphology and structure of the composite microspheres. After filling into polystyrene (PS), a segregated structure of (rGO@SBA) that enables a concentrated aggregation of rGO in SBA was fabricated. The dielectric permittivity of PS could reach 10.91 (at 1 KHz) by incorporating only 0.39 wt% rGO by using this segregated structure of (rGO@SBA). PS simply mixed with SBA microspheres and graphite (PS/rGO-SBA) was also fabricated as a comparison group to verify the effect of this segregated structure on the dielectric properties of the composites. After comparing the dielectric properties of PS composites with different structures, the enhancement in dielectric permittivity of the composites can be demonstrated.