Detalhe da pesquisa
1.
Engineering the Relatively Conserved Residues in Active Site Architecture of Thermophilic Chitinase SsChi18A Enhanced Catalytic Activity.
Biomacromolecules
; 25(1): 238-247, 2024 01 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-38116793
2.
Gasdermin E regulates the stability and activation of EGFR in human non-small cell lung cancer cells.
Cell Commun Signal
; 21(1): 83, 2023 04 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-37085908
3.
Loop Evolutionary Patterns Shape Catalytic Efficiency of TRI101/201 for Trichothecenes: Insights into Protein-Substrate Interactions.
J Chem Inf Model
; 63(20): 6316-6331, 2023 10 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-37821422
4.
Inwardly rectifying potassium channels mediate polymyxin-induced nephrotoxicity.
Cell Mol Life Sci
; 79(6): 296, 2022 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35570209
5.
Data-driven strategies for the computational design of enzyme thermal stability: trends, perspectives, and prospects.
Acta Biochim Biophys Sin (Shanghai)
; 55(3): 343-355, 2023 Mar 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-37143326
6.
Molecular Dynamics Simulations Reveal the Conformational Transition of GH33 Sialidases.
Int J Mol Sci
; 24(7)2023 Apr 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37047800
7.
Simulations of octapeptin-outer membrane interactions reveal conformational flexibility is linked to antimicrobial potency.
J Biol Chem
; 295(47): 15902-15912, 2020 11 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-32913118
8.
Antimicrobial Peptides: An Update on Classifications and Databases.
Int J Mol Sci
; 22(21)2021 Oct 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-34769122
9.
Molecular dynamics simulations informed by membrane lipidomics reveal the structure-interaction relationship of polymyxins with the lipid A-based outer membrane of Acinetobacter baumannii.
J Antimicrob Chemother
; 75(12): 3534-3543, 2020 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32911540
10.
Converting a ß-N-acetylhexosaminidase into two trans-ß-N-acetylhexosaminidases by domain-targeted mutagenesis.
Appl Microbiol Biotechnol
; 104(2): 661-673, 2020 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-31822984
11.
Three glycoside hydrolase family 12 enzymes display diversity in substrate specificities and synergistic action between each other.
Mol Biol Rep
; 46(5): 5443-5454, 2019 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-31359382
12.
Enhancement in catalytic activity of Aspergillus niger XynB by selective site-directed mutagenesis of active site amino acids.
Appl Microbiol Biotechnol
; 102(1): 249-260, 2018 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-29103167
13.
Substrate binding interferes with active site conformational dynamics in endoglucanase Cel5A from Thermobifida fusca.
Biochem Biophys Res Commun
; 491(1): 236-240, 2017 09 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-28720496
14.
Dynamic Perturbation of the Active Site Determines Reversible Thermal Inactivation in Glycoside Hydrolase Family 12.
J Chem Inf Model
; 57(2): 288-297, 2017 02 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-28145703
15.
Structural and dynamic evolution of the amphipathic N-terminus diversifies enzyme thermostability in the glycoside hydrolase family 12.
Phys Chem Chem Phys
; 18(31): 21340-50, 2016 Aug 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-27425569
16.
Two natural compounds as potential inhibitors against the Helicobacter pylori and Acinetobacter baumannii IspD enzymes.
Int J Antimicrob Agents
; 63(5): 107160, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38537721
17.
Molecular dynamics simulations identify the topological weak spots of a protease CN2S8A.
J Mol Graph Model
; 124: 108571, 2023 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37487372
18.
Dynamics of loops surrounding the active site architecture in GH5_2 subfamily TfCel5A for cellulose degradation.
Biotechnol Biofuels Bioprod
; 16(1): 154, 2023 Oct 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-37853500
19.
Molecular Insights to the Structure-Interaction Relationships of Human Proton-Coupled Oligopeptide Transporters (PepTs).
Pharmaceutics
; 15(10)2023 Oct 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-37896276
20.
Critical Role of Position 10 Residue in the Polymyxin Antimicrobial Activity.
J Med Chem
; 66(4): 2865-2876, 2023 02 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-36745479