Detalhe da pesquisa
1.
Hypoxic activation of glucose-6-phosphate dehydrogenase controls the expression of genes involved in the pathogenesis of pulmonary hypertension through the regulation of DNA methylation.
Am J Physiol Lung Cell Mol Physiol
; 318(4): L773-L786, 2020 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32159369
2.
Elevated 20-HETE in metabolic syndrome regulates arterial stiffness and systolic hypertension via MMP12 activation.
J Mol Cell Cardiol
; 117: 88-99, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29428638
3.
Cyp2c44 gene disruption is associated with increased hematopoietic stem cells: implication in chronic hypoxia-induced pulmonary hypertension.
Am J Physiol Heart Circ Physiol
; 313(2): H293-H303, 2017 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28550179
4.
MicroRNA-140 is elevated and mitofusin-1 is downregulated in the right ventricle of the Sugen5416/hypoxia/normoxia model of pulmonary arterial hypertension.
Am J Physiol Heart Circ Physiol
; 311(3): H689-98, 2016 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27422986
5.
20-HETE-induced mitochondrial superoxide production and inflammatory phenotype in vascular smooth muscle is prevented by glucose-6-phosphate dehydrogenase inhibition.
Am J Physiol Heart Circ Physiol
; 310(9): H1107-17, 2016 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26921441
6.
Vascular smooth muscle cell contractile protein expression is increased through protein kinase G-dependent and -independent pathways by glucose-6-phosphate dehydrogenase inhibition and deficiency.
Am J Physiol Heart Circ Physiol
; 311(4): H904-H912, 2016 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27521420
7.
Glucose-6-phosphate dehydrogenase plays a critical role in hypoxia-induced CD133+ progenitor cells self-renewal and stimulates their accumulation in the lungs of pulmonary hypertensive rats.
Am J Physiol Lung Cell Mol Physiol
; 307(7): L545-56, 2014 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25063801
8.
Corrigendum to "Elevated 20-HETE in metabolic syndrome regulates arterial stiffness and systolic hypertension via MMP12 activation" [J. Mol. Cell. Cardiol. 117 (2018) 88-99].
J Mol Cell Cardiol
; 121: 308, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29625729
9.
Cyp2c44 gene disruption exacerbated pulmonary hypertension and heart failure in female but not male mice.
Pulm Circ
; 6(3): 360-8, 2016 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-27683613