Detalhe da pesquisa
1.
Nanobodies as allosteric modulators of Parkinson's disease-associated LRRK2.
Proc Natl Acad Sci U S A
; 119(9)2022 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35217606
2.
Targeting Rab-RILPL interactions as a strategy to downregulate pathogenic LRRK2 in Parkinson's disease.
J Pept Sci
; 30(5): e3563, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38135900
3.
Mitotic spindle association of TACC3 requires Aurora-A-dependent stabilization of a cryptic α-helix.
EMBO J
; 37(8)2018 04 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-29510984
4.
Targeting the WASF3 complex to suppress metastasis.
Pharmacol Res
; 182: 106302, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35691539
5.
Protein kinase A-mediated phosphorylation of naked cuticle homolog 2 stimulates cell-surface delivery of transforming growth factor-α for epidermal growth factor receptor transactivation.
Traffic
; 20(5): 357-368, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30941853
6.
Genetically encoded biosensors for visualizing live-cell biochemical activity at super-resolution.
Nat Methods
; 14(4): 427-434, 2017 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-28288122
7.
Targeting Plasmodium with constrained peptides and peptidomimetics.
IUBMB Life
; 72(6): 1103-1114, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32037730
8.
Hydrophobic Core Variations Provide a Structural Framework for Tyrosine Kinase Evolution and Functional Specialization.
PLoS Genet
; 12(2): e1005885, 2016 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-26925779
9.
Correction: Hydrophobic Core Variations Provide a Structural Framework for Tyrosine Kinase Evolution and Functional Specialization.
PLoS Genet
; 12(8): e1006265, 2016 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-27513745
10.
A Stapled Peptide Mimic of the Pseudosubstrate Inhibitor PKI Inhibits Protein Kinase A.
Molecules
; 24(8)2019 Apr 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-31009996
11.
Cell penetrating peptides to dissect host-pathogen protein-protein interactions in Theileria-transformed leukocytes.
Bioorg Med Chem
; 26(6): 1127-1134, 2018 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28917447
12.
Conformationally constrained peptides target the allosteric kinase dimer interface and inhibit EGFR activation.
Bioorg Med Chem
; 26(6): 1167-1173, 2018 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28911855
13.
Investigating PKA-RII specificity using analogs of the PKA:AKAP peptide inhibitor STAD-2.
Bioorg Med Chem
; 26(6): 1174-1178, 2018 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29449124
14.
Persistent Electrical Activity in Primary Nociceptors after Spinal Cord Injury Is Maintained by Scaffolded Adenylyl Cyclase and Protein Kinase A and Is Associated with Altered Adenylyl Cyclase Regulation.
J Neurosci
; 36(5): 1660-8, 2016 Feb 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-26843647
15.
AKAP18:PKA-RIIα structure reveals crucial anchor points for recognition of regulatory subunits of PKA.
Biochem J
; 473(13): 1881-94, 2016 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27102985
16.
Structural and evolutionary divergence of cyclic nucleotide binding domains in eukaryotic pathogens: Implications for drug design.
Biochim Biophys Acta
; 1854(10 Pt B): 1575-85, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-25847873
17.
Neurochondrin is an atypical RIIα-specific A-kinase anchoring protein.
Biochim Biophys Acta
; 1854(10 Pt B): 1667-75, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-25916936
18.
Defining A-Kinaseâ Anchoring Protein (AKAP) Specificity for the Protein Kinaseâ A Subunit RI (PKA-RI).
Chembiochem
; 17(8): 693-697, 2016 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26611881
19.
Design of a selenylsulfide-bridged EGFR dimerization arm mimic.
Bioorg Med Chem
; 23(12): 2761-6, 2015 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25840798
20.
EMBO conference series: Chemical Biology 2014.
Chembiochem
; 15(18): 2783-7, 2014 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25318996