Detalhe da pesquisa
1.
p21-activated kinase 4 inhibition protects against liver ischemia/reperfusion injury: Role of nuclear factor erythroid 2-related factor 2 phosphorylation.
Hepatology
; 76(2): 345-356, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35108418
2.
Discovery of a selective inhibitor of doublecortin like kinase 1.
Nat Chem Biol
; 16(6): 635-643, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32251410
3.
Puerarin attenuates hepatic steatosis via G-protein-coupled estrogen receptor-mediated calcium and SIRT1 signaling pathways.
Phytother Res
; 36(9): 3601-3618, 2022 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-35871535
4.
Novel Quercetin Derivative of 3,7-Dioleylquercetin Shows Less Toxicity and Highly Potent Tyrosinase Inhibition Activity.
Int J Mol Sci
; 22(8)2021 Apr 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-33923988
5.
Acacetin Inhibits the Growth of STAT3-Activated DU145 Prostate Cancer Cells by Directly Binding to Signal Transducer and Activator of Transcription 3 (STAT3).
Molecules
; 26(20)2021 Oct 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-34684783
6.
Targeting transcription regulation in cancer with a covalent CDK7 inhibitor.
Nature
; 511(7511): 616-20, 2014 Jul 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-25043025
7.
Synthesis and structure activity relationships of a series of 4-amino-1H-pyrazoles as covalent inhibitors of CDK14.
Bioorg Med Chem Lett
; 29(15): 1985-1993, 2019 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31175010
8.
BCPA {N,N'-1,4-Butanediylbis[3-(2-chlorophenyl)acrylamide]} Inhibits Osteoclast Differentiation through Increased Retention of Peptidyl-Prolyl cis-trans Isomerase Never in Mitosis A-Interacting 1.
Int J Mol Sci
; 19(11)2018 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30388885
9.
DPIE [2-(1,2-diphenyl-1H-indol-3-yl)ethanamine] Augments Pro-Inflammatory Cytokine Production in IL-1ß-Stimulated Primary Human Oral Cells.
Int J Mol Sci
; 19(7)2018 Jun 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-29932110
10.
Inhibitory Effects of 2N1HIA (2-(3-(2-Fluoro-4-Methoxyphenyl)-6-Oxo-1(6H)-Pyridazinyl)-N-1H-Indol-5-Ylacetamide) on Osteoclast Differentiation via Suppressing Cathepsin K Expression.
Molecules
; 23(12)2018 Nov 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-30501117
11.
Expression and purification of biologically active recombinant human paraoxonase 1 from a Drosophila S2 stable cell line.
Protein Expr Purif
; 131: 34-41, 2017 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-27838376
12.
Identification of TG100-115 as a new and potent TRPM7 kinase inhibitor, which suppresses breast cancer cell migration and invasion.
Biochim Biophys Acta Gen Subj
; 1861(4): 947-957, 2017 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-28161478
13.
Characterization of a highly selective inhibitor of the Aurora kinases.
Bioorg Med Chem Lett
; 27(18): 4405-4408, 2017 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28818446
14.
The Application of REDOR NMR to Understand the Conformation of Epothilone B.
Int J Mol Sci
; 18(7)2017 Jul 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-28698492
15.
Identification of a Small Benzamide Inhibitor of Influenza Virus Using a Cell-Based Screening.
Chemotherapy
; 61(3): 159-66, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-26821172
16.
Identification of Selective ERRγ Inverse Agonists.
Molecules
; 21(1): 80, 2016 Jan 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-26771593
17.
Development of a mitochondria-targeted Hsp90 inhibitor based on the crystal structures of human TRAP1.
J Am Chem Soc
; 137(13): 4358-67, 2015 Apr 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-25785725
18.
In vitro metabolism of an estrogen-related receptor γ modulator, GSK5182, by human liver microsomes and recombinant cytochrome P450s.
Biopharm Drug Dispos
; 36(3): 163-73, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25451157
19.
Therapeutic targeting of oncogenic K-Ras by a covalent catalytic site inhibitor.
Angew Chem Int Ed Engl
; 53(1): 199-204, 2014 Jan 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-24259466
20.
p21-activated kinase 4 counteracts PKA-dependent lipolysis by phosphorylating FABP4 and HSL.
Nat Metab
; 6(1): 94-112, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-38216738