Detalhe da pesquisa
1.
Optimizing tuberculosis treatment efficacy: Comparing the standard regimen with Moxifloxacin-containing regimens.
PLoS Comput Biol
; 19(6): e1010823, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37319311
2.
A virtual host model of Mycobacterium tuberculosis infection identifies early immune events as predictive of infection outcomes.
J Theor Biol
; 539: 111042, 2022 04 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-35114195
3.
IL-10 Impairs Local Immune Response in Lung Granulomas and Lymph Nodes during Early Mycobacterium tuberculosis Infection.
J Immunol
; 204(3): 644-659, 2020 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31862711
4.
Structural identifiability analysis of age-structured PDE epidemic models.
J Math Biol
; 84(1-2): 9, 2022 01 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-34982260
5.
Dynamic balance of pro- and anti-inflammatory signals controls disease and limits pathology.
Immunol Rev
; 285(1): 147-167, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-30129209
6.
Systems biology predicts that fibrosis in tuberculous granulomas may arise through macrophage-to-myofibroblast transformation.
PLoS Comput Biol
; 16(12): e1008520, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33370784
7.
A computational model tracks whole-lung Mycobacterium tuberculosis infection and predicts factors that inhibit dissemination.
PLoS Comput Biol
; 16(5): e1007280, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32433646
8.
Predicting the second wave of COVID-19 in Washtenaw County, MI.
J Theor Biol
; 507: 110461, 2020 12 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-32866493
9.
A Framework for Network-Based Epidemiological Modeling of Tuberculosis Dynamics Using Synthetic Datasets.
Bull Math Biol
; 82(6): 78, 2020 06 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-32535697
10.
Fluoroquinolone Efficacy against Tuberculosis Is Driven by Penetration into Lesions and Activity against Resident Bacterial Populations.
Antimicrob Agents Chemother
; 63(5)2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30803965
11.
Evaluating vaccination strategies for tuberculosis in endemic and non-endemic settings.
J Theor Biol
; 469: 1-11, 2019 05 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-30851550
12.
Dose finding for new vaccines: The role for immunostimulation/immunodynamic modelling.
J Theor Biol
; 465: 51-55, 2019 03 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-30639297
13.
Data-Driven Model Validation Across Dimensions.
Bull Math Biol
; 81(6): 1853-1866, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30830675
14.
Low Levels of T Cell Exhaustion in Tuberculous Lung Granulomas.
Infect Immun
; 86(9)2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29891540
15.
Comparing efficacies of moxifloxacin, levofloxacin and gatifloxacin in tuberculosis granulomas using a multi-scale systems pharmacology approach.
PLoS Comput Biol
; 13(8): e1005650, 2017 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-28817561
16.
Variability in tuberculosis granuloma T cell responses exists, but a balance of pro- and anti-inflammatory cytokines is associated with sterilization.
PLoS Pathog
; 11(1): e1004603, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25611466
17.
Identifying mechanisms driving formation of granuloma-associated fibrosis during Mycobacterium tuberculosis infection.
J Theor Biol
; 429: 1-17, 2017 09 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-28642013
18.
Computational and Empirical Studies Predict Mycobacterium tuberculosis-Specific T Cells as a Biomarker for Infection Outcome.
PLoS Comput Biol
; 12(4): e1004804, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-27065304
19.
Computational modeling predicts IL-10 control of lesion sterilization by balancing early host immunity-mediated antimicrobial responses with caseation during mycobacterium tuberculosis infection.
J Immunol
; 194(2): 664-77, 2015 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25512604
20.
Multiscale Model of Mycobacterium tuberculosis Infection Maps Metabolite and Gene Perturbations to Granuloma Sterilization Predictions.
Infect Immun
; 84(5): 1650-1669, 2016 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-26975995