Detalhe da pesquisa
1.
Rapamycin nanoparticles increase the therapeutic window of engineered interleukin-2 and drive expansion of antigen-specific regulatory T cells for protection against autoimmune disease.
J Autoimmun
; 140: 103125, 2023 Oct 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-37844543
2.
Tolerogenic nanoparticles restore the antitumor activity of recombinant immunotoxins by mitigating immunogenicity.
Proc Natl Acad Sci U S A
; 115(4): E733-E742, 2018 01 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-29311317
3.
Polymeric synthetic nanoparticles for the induction of antigen-specific immunological tolerance.
Proc Natl Acad Sci U S A
; 112(2): E156-65, 2015 Jan 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-25548186
4.
Readministration of high-dose adeno-associated virus gene therapy vectors enabled by ImmTOR nanoparticles combined with B cell-targeted agents.
PNAS Nexus
; 2(11): pgad394, 2023 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-38024395
5.
Tolerogenic nanoparticles mitigate the formation of anti-drug antibodies against pegylated uricase in patients with hyperuricemia.
Nat Commun
; 13(1): 272, 2022 01 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35022448
6.
Outbreak of adverse reactions associated with contaminated heparin.
N Engl J Med
; 359(25): 2674-84, 2008 Dec 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-19052120
7.
Contaminated heparin associated with adverse clinical events and activation of the contact system.
N Engl J Med
; 358(23): 2457-67, 2008 Jun 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-18434646
8.
ImmTORTM to amplify the efficacy and reduce immunogenicity of biologics.
Emerg Top Life Sci
; 5(5): 597-600, 2021 11 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34387325
9.
Enhancement of the Tolerogenic Phenotype in the Liver by ImmTOR Nanoparticles.
Front Immunol
; 12: 637469, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34113339
10.
ImmTOR nanoparticles enhance AAV transgene expression after initial and repeat dosing in a mouse model of methylmalonic acidemia.
Mol Ther Methods Clin Dev
; 22: 279-292, 2021 Sep 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34485611
11.
Long-term correction of ornithine transcarbamylase deficiency in Spf-Ash mice with a translationally optimized AAV vector.
Mol Ther Methods Clin Dev
; 20: 169-180, 2021 Mar 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33473356
12.
Development of ImmTOR Tolerogenic Nanoparticles for the Mitigation of Anti-drug Antibodies.
Front Immunol
; 11: 969, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32508839
13.
Nanoparticles for the Induction of Antigen-Specific Immunological Tolerance.
Front Immunol
; 9: 230, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29515571
14.
Synthetic vaccine particles for durable cytolytic T lymphocyte responses and anti-tumor immunotherapy.
PLoS One
; 13(6): e0197694, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29856772
15.
Antigen-selective modulation of AAV immunogenicity with tolerogenic rapamycin nanoparticles enables successful vector re-administration.
Nat Commun
; 9(1): 4098, 2018 10 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30291246
16.
Addressing high dose AAV toxicity - 'one and done' or 'slower and lower'?
Expert Opin Biol Ther
; 22(9): 1067-1071, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35373689
17.
Generation of a universal CD4 memory T cell recall peptide effective in humans, mice and non-human primates.
Vaccine
; 32(24): 2896-903, 2014 May 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-24583006
18.
Adjuvant-carrying synthetic vaccine particles augment the immune response to encapsulated antigen and exhibit strong local immune activation without inducing systemic cytokine release.
Vaccine
; 32(24): 2882-95, 2014 May 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-24593999
19.
M402, a novel heparan sulfate mimetic, targets multiple pathways implicated in tumor progression and metastasis.
PLoS One
; 6(6): e21106, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-21698156
20.
Non-invasive detection of a small number of bioluminescent cancer cells in vivo.
PLoS One
; 5(2): e9364, 2010 Feb 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-20186331