Detalhe da pesquisa
1.
REDD1 loss reprograms lipid metabolism to drive progression of RAS mutant tumors.
Genes Dev
; 34(11-12): 751-766, 2020 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32273287
2.
A quantitative FastFUCCI assay defines cell cycle dynamics at a single-cell level.
J Cell Sci
; 130(2): 512-520, 2017 01 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27888217
3.
Modelling of the cancer cell cycle as a tool for rational drug development: A systems pharmacology approach to cyclotherapy.
PLoS Comput Biol
; 13(5): e1005529, 2017 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28467408
4.
Mathematical imaging methods for mitosis analysis in live-cell phase contrast microscopy.
Methods
; 115: 91-99, 2017 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28189773
5.
Signaling dynamics of DNA damage response invoked by combination therapy are dose-dependent.
J Biol Chem
; 294(6): 2191, 2019 02 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30737318
6.
Meiotic protein SYCP2 confers resistance to DNA-damaging agents through R-loop-mediated DNA repair.
Nat Commun
; 15(1): 1568, 2024 Feb 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-38383600
7.
Regulation of RNA methylation by therapy treatment, promotes tumor survival.
bioRxiv
; 2023 May 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-37292633
8.
The expanding role of WEE1.
Cell Signal
; 94: 110310, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35304285
9.
Immune activation and evolution through chemotherapy plus checkpoint blockade in triple-negative breast cancer.
Cancer Cell
; 39(12): 1562-1564, 2021 12 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-34767761
10.
Prediction and identification of synergistic compound combinations against pancreatic cancer cells.
iScience
; 24(9): 103080, 2021 Sep 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-34585118
11.
Systematic tissue collection during clinical breast biopsy is feasible, safe and enables high-content translational analyses.
NPJ Precis Oncol
; 5(1): 85, 2021 Sep 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-34548623
12.
RASAL2 Confers Collateral MEK/EGFR Dependency in Chemoresistant Triple-Negative Breast Cancer.
Clin Cancer Res
; 27(17): 4883-4897, 2021 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34168046
13.
Author Correction: Meiotic protein SYCP2 confers resistance to DNA-damaging agents through R-loop-mediated DNA repair.
Nat Commun
; 15(1): 3819, 2024 May 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-38714829
14.
The ATR Inhibitor AZD6738 Synergizes with Gemcitabine In Vitro and In Vivo to Induce Pancreatic Ductal Adenocarcinoma Regression.
Mol Cancer Ther
; 17(8): 1670-1682, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29891488
15.
Mechanistic Distinctions between CHK1 and WEE1 Inhibition Guide the Scheduling of Triple Therapy with Gemcitabine.
Cancer Res
; 78(11): 3054-3066, 2018 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29735549
16.
An automated fitting procedure and software for dose-response curves with multiphasic features.
Sci Rep
; 5: 14701, 2015 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26424192
17.
CHK1 Inhibition Synergizes with Gemcitabine Initially by Destabilizing the DNA Replication Apparatus.
Cancer Res
; 75(17): 3583-95, 2015 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26141863
18.
Curcumin analogues with potent and selective anti-proliferative activity on acute promyelocytic leukemia: involvement of accumulated misfolded nuclear receptor co-repressor (N-CoR) protein as a basis for selective activity.
ChemMedChem
; 7(9): 1567-79, 2012 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-22887959
19.
Exploration and optimization of structure-activity relationships in drug design using the Taguchi method.
ChemMedChem
; 7(6): 977-82, 2012 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-22555964