Detalhe da pesquisa
1.
Danicamtiv Increases Myosin Recruitment and Alters Cross-Bridge Cycling in Cardiac Muscle.
Circ Res
; 133(5): 430-443, 2023 08 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-37470183
2.
MYBPC3-c.772G>A mutation results in haploinsufficiency and altered myosin cycling kinetics in a patient induced stem cell derived cardiomyocyte model of hypertrophic cardiomyopathy.
J Mol Cell Cardiol
; 191: 27-39, 2024 Apr 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-38648963
3.
Altered Cardiac Energetics and Mitochondrial Dysfunction in Hypertrophic Cardiomyopathy.
Circulation
; 144(21): 1714-1731, 2021 11 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-34672721
4.
4HNE Impairs Myocardial Bioenergetics in Congenital Heart Disease-Induced Right Ventricular Failure.
Circulation
; 142(17): 1667-1683, 2020 10 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-32806952
5.
Point mutations in the tri-helix bundle of the M-domain of cardiac myosin binding protein-C influence systolic duration and delay cardiac relaxation.
J Mol Cell Cardiol
; 119: 116-124, 2018 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29729251
6.
Machine learning meets Monte Carlo methods for models of muscle's molecular machinery to classify mutations.
J Gen Physiol
; 155(5)2023 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37000171
7.
Hypertrophic cardiomyopathy in purpose-bred cats with the A31P mutation in cardiac myosin binding protein-C.
Sci Rep
; 13(1): 10319, 2023 06 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-37365215
8.
Danicamtiv increases myosin recruitment and alters the chemomechanical cross bridge cycle in cardiac muscle.
bioRxiv
; 2023 Feb 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36778318
9.
Correcting dilated cardiomyopathy with fibroblast-targeted p38 deficiency.
bioRxiv
; 2023 Jan 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-36747691
10.
Modulating the tension-time integral of the cardiac twitch prevents dilated cardiomyopathy in murine hearts.
JCI Insight
; 5(20)2020 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32931484
11.
ß-Cardiac myosin hypertrophic cardiomyopathy mutations release sequestered heads and increase enzymatic activity.
Nat Commun
; 10(1): 2685, 2019 06 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-31213605
12.
miR-21 is associated with fibrosis and right ventricular failure.
JCI Insight
; 2(9)2017 May 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28469078
13.
Early-Onset Hypertrophic Cardiomyopathy Mutations Significantly Increase the Velocity, Force, and Actin-Activated ATPase Activity of Human ß-Cardiac Myosin.
Cell Rep
; 17(11): 2857-2864, 2016 12 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-27974200