Detalhe da pesquisa
1.
Mitochondrial clearance and maturation of autophagosomes are compromised in LRRK2 G2019S familial Parkinson's disease patient fibroblasts.
Hum Mol Genet
; 28(19): 3232-3243, 2019 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31261377
2.
Repulsive Guidance Molecule a (RGMa) Induces Neuropathological and Behavioral Changes That Closely Resemble Parkinson's Disease.
J Neurosci
; 37(39): 9361-9379, 2017 09 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-28842419
3.
Crucial neuroprotective roles of the metabolite BH4 in dopaminergic neurons.
bioRxiv
; 2023 May 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37214873
4.
The proliferative capacity of the subventricular zone is maintained in the parkinsonian brain.
Brain
; 134(Pt 11): 3249-63, 2011 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-22075520
5.
Upregulating ß-hexosaminidase activity in rodents prevents α-synuclein lipid associations and protects dopaminergic neurons from α-synuclein-mediated neurotoxicity.
Acta Neuropathol Commun
; 8(1): 127, 2020 08 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32762772
6.
Splice-Switching Antisense Oligonucleotides Reduce LRRK2 Kinase Activity in Human LRRK2 Transgenic Mice.
Mol Ther Nucleic Acids
; 21: 623-635, 2020 Sep 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32736291
7.
Neurite Collapse and Altered ER Ca2+ Control in Human Parkinson Disease Patient iPSC-Derived Neurons with LRRK2 G2019S Mutation.
Stem Cell Reports
; 12(1): 29-41, 2019 01 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30595548
8.
Small Scale Production of Recombinant Adeno-Associated Viral Vectors for Gene Delivery to the Nervous System.
Methods Mol Biol
; 1715: 3-17, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29188502
9.
Modeling early Parkinson's disease pathology with chronic low dose MPTP treatment.
Restor Neurol Neurosci
; 31(2): 155-67, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23271419
10.
Phenotypic characterization of retinoic acid differentiated SH-SY5Y cells by transcriptional profiling.
PLoS One
; 8(5): e63862, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23724009
11.
Cell-replacement and gene-therapy strategies for Parkinson's and Alzheimer's disease.
Regen Med
; 2(4): 425-46, 2007 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-17635050