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Phys Med Biol ; 62(20): 8136-8153, 2017 Oct 04.
Artigo em Inglês | MEDLINE | ID: mdl-28817381

RESUMO

A novel breathing phantom was designed for being used in conventional and ion-beam radiotherapy as well as for medical imaging. Accurate dose delivery and patient safety are aimed to be verified for four-dimensional (4D) treatment techniques compensating for breathing-induced tumor motion. The phantom includes anthropomorphic components representing an average human thorax. It consists of real tissue equivalent materials to fulfill the requirements for dosimetric experiments and imaging purposes. The different parts of the torso (lungs, chest wall, and ribs) and the tumor can move independently. Simple regular movements, as well as more advanced patient-specific breathing cycles are feasible while a reproducible setup can be guaranteed. The phantom provides the flexibility to use different types of dosimetric devices and was designed in a way that it is robust, transportable and easy to handle. Tolerance levels and the reliability of the phantom setup were determined in combination with tests on motion accuracy and reproducibility by using infrared optical tracking technology. Different imaging was performed including positron emission tomography imaging, 4D computed tomography as well as real-time in-room imaging. The initial dosimetric benchmarking studies were performed in a photon beam where dose parameters are predictable and the dosimetric procedures well established.


Assuntos
Tomografia Computadorizada Quadridimensional/métodos , Neoplasias Pulmonares/radioterapia , Movimento/fisiologia , Imagens de Fantasmas , Planejamento da Radioterapia Assistida por Computador/métodos , Respiração , Técnicas de Imagem de Sincronização Respiratória/métodos , Humanos , Pulmão/diagnóstico por imagem , Neoplasias Pulmonares/diagnóstico por imagem , Tomografia por Emissão de Pósitrons/métodos , Radiometria/métodos , Reprodutibilidade dos Testes , Tórax/diagnóstico por imagem
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