Detalhe da pesquisa
1.
NUTS and BOLTS: applications of fluorescence-detected sedimentation.
Anal Biochem
; 390(1): 1-13, 2009 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19103145
2.
Discovery and characterization of the N-phenyl-N'-naphthylurea class of p38 kinase inhibitors.
Bioorg Med Chem Lett
; 19(9): 2386-91, 2009 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19356929
3.
Discovery and optimization of p38 inhibitors via computer-assisted drug design.
J Med Chem
; 50(17): 4016-26, 2007 Aug 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-17658737
4.
Agonist versus antagonist induce distinct thermodynamic modes of co-factor binding to the glucocorticoid receptor.
Biophys Chem
; 128(2-3): 156-64, 2007 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-17466438
5.
Small molecule LFA-1 antagonists compete with an anti-LFA-1 monoclonal antibody for binding to the CD11a I domain: development of a flow-cytometry-based receptor occupancy assay.
J Immunol Methods
; 277(1-2): 101-15, 2003 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-12799043
6.
Thermal denaturation: a method to rank slow binding, high-affinity P38alpha MAP kinase inhibitors.
J Med Chem
; 46(22): 4669-75, 2003 Oct 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-14561086
7.
Structure-activity relationships of the p38alpha MAP kinase inhibitor 1-(5-tert-butyl-2-p-tolyl-2H-pyrazol-3-yl)-3-[4-(2-morpholin-4-yl-ethoxy)naph- thalen-1-yl]urea (BIRB 796).
J Med Chem
; 46(22): 4676-86, 2003 Oct 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-14561087
8.
New modifications to the area of pyrazole-naphthyl urea based p38 MAP kinase inhibitors that bind to the adenine/ATP site.
Bioorg Med Chem Lett
; 17(15): 4242-7, 2007 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17560108
9.
Discovery and design of benzimidazolone based inhibitors of p38 MAP kinase.
Bioorg Med Chem Lett
; 16(24): 6316-20, 2006 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17010605
10.
Assembly of major histocompatibility complex (MHC) class II transcription factors: association and promoter recognition of RFX proteins.
Biochemistry
; 43(40): 12750-60, 2004 Oct 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-15461447
11.
Discovery and characterization of a substrate selective p38alpha inhibitor.
Biochemistry
; 43(37): 11658-71, 2004 Sep 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-15362850
12.
Catalysis and function of the p38 alpha.MK2a signaling complex.
Biochemistry
; 43(31): 9950-60, 2004 Aug 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-15287722