Detalhe da pesquisa
1.
Beyond Erectile Dysfunction: cGMP-Specific Phosphodiesterase 5 Inhibitors for Other Clinical Disorders.
Annu Rev Pharmacol Toxicol
; 63: 585-615, 2023 Jan 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-36206989
2.
Androgen-deprivation therapy with leuprolide increases abdominal adiposity without causing cardiac dysfunction in middle-aged male mice: effect of sildenafil.
Am J Physiol Regul Integr Comp Physiol
; 324(4): R589-R600, 2023 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36878484
3.
Treating diabetes with combination of phosphodiesterase 5 inhibitors and hydroxychloroquine-a possible prevention strategy for COVID-19?
Mol Cell Biochem
; 478(3): 679-696, 2023 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-36036333
4.
Physiological effects of ivabradine in heart failure and beyond.
Mol Cell Biochem
; 2023 Sep 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-37768496
5.
Single-Dose Treatment with Rapamycin Preserves Post-Ischemic Cardiac Function through Attenuation of Fibrosis and Inflammation in Diabetic Rabbit.
Int J Mol Sci
; 24(10)2023 May 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-37240345
6.
Regulatory role of mammalian target of rapamycin signaling in exosome secretion and osteogenic changes in smooth muscle cells lacking acid ceramidase gene.
FASEB J
; 35(7): e21732, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34143450
7.
Chronic inhibition of phosphodiesterase 5 with tadalafil affords cardioprotection in a mouse model of metabolic syndrome: role of nitric oxide.
Mol Cell Biochem
; 468(1-2): 47-58, 2020 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-32162053
8.
PDE5 inhibitor sildenafil attenuates cardiac microRNA 214 upregulation and pro-apoptotic signaling after chronic alcohol ingestion in mice.
Mol Cell Biochem
; 471(1-2): 189-201, 2020 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-32535704
9.
Beyond Hepatoprotection-The Cardioprotective Effects of Bicyclol in Diabetes.
Cardiovasc Drugs Ther
; 2023 Dec 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-38055185
10.
Irradiation-Induced Cardiac Connexin-43 and miR-21 Responses Are Hampered by Treatment with Atorvastatin and Aspirin.
Int J Mol Sci
; 19(4)2018 Apr 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-29642568
11.
PDE5 Inhibitor Tadalafil and Hydroxychloroquine Cotreatment Provides Synergistic Protection against Type 2 Diabetes and Myocardial Infarction in Mice.
J Pharmacol Exp Ther
; 361(1): 29-38, 2017 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28123046
12.
Corticosteroids and aldose reductase inhibitor Epalrestat modulates cardiac action potential via Kvß1.1 (AKR6A8) subunit of voltage-gated potassium channel.
Mol Cell Biochem
; 436(1-2): 71-78, 2017 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-28585087
13.
The NHLBI-sponsored Consortium for preclinicAl assESsment of cARdioprotective therapies (CAESAR): a new paradigm for rigorous, accurate, and reproducible evaluation of putative infarct-sparing interventions in mice, rabbits, and pigs.
Circ Res
; 116(4): 572-86, 2015 Feb 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-25499773
14.
Long-acting PDE5 inhibitor tadalafil prevents early doxorubicin-induced left ventricle diastolic dysfunction in juvenile mice: potential role of cytoskeletal proteins.
Can J Physiol Pharmacol
; 95(3): 295-304, 2017 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-28238269
15.
Potential markers and metabolic processes involved in the mechanism of radiation-induced heart injury.
Can J Physiol Pharmacol
; 95(10): 1190-1203, 2017 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-28750189
16.
Beet root juice protects against doxorubicin toxicity in cardiomyocytes while enhancing apoptosis in breast cancer cells.
Mol Cell Biochem
; 421(1-2): 89-101, 2016 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-27565811
17.
Targeted Inhibition of Phosphoinositide 3-Kinase/Mammalian Target of Rapamycin Sensitizes Pancreatic Cancer Cells to Doxorubicin without Exacerbating Cardiac Toxicity.
Mol Pharmacol
; 88(3): 512-23, 2015 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-26101222
18.
Mammalian target of rapamycin (mTOR) inhibition with rapamycin improves cardiac function in type 2 diabetic mice: potential role of attenuated oxidative stress and altered contractile protein expression.
J Biol Chem
; 289(7): 4145-60, 2014 Feb 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-24371138
19.
Hydrogen sulfide mediates the cardioprotective effects of gene therapy with PKG-Iα.
Basic Res Cardiol
; 110(4): 42, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26036467
20.
Inhibition of mammalian target of rapamycin protects against reperfusion injury in diabetic heart through STAT3 signaling.
Basic Res Cardiol
; 110(3): 31, 2015 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-25911189