Detalhe da pesquisa
1.
Posttranscriptional regulation of FAN1 by miR-124-3p at rs3512 underlies onset-delaying genetic modification in Huntington's disease.
Proc Natl Acad Sci U S A
; 121(16): e2322924121, 2024 Apr 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-38607933
2.
Huntingtin turnover: modulation of huntingtin degradation by cAMP-dependent protein kinase A (PKA) phosphorylation of C-HEAT domain Ser2550.
Hum Mol Genet
; 32(1): 30-45, 2023 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35908190
3.
Genetic modifiers of Huntington disease differentially influence motor and cognitive domains.
Am J Hum Genet
; 109(5): 885-899, 2022 05 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35325614
4.
Probing Local pH Change during Electrode Oxidation of TEMPO Derivative: Implication of Redox-Induced Acidity Alternation by Imidazolium-Linker Functional Groups.
Anal Chem
; 96(14): 5537-5545, 2024 Apr 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-38545995
5.
Mutations causing Lopes-Maciel-Rodan syndrome are huntingtin hypomorphs.
Hum Mol Genet
; 30(3-4): 135-148, 2021 04 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-33432339
6.
Genetic and Functional Analyses Point to FAN1 as the Source of Multiple Huntington Disease Modifier Effects.
Am J Hum Genet
; 107(1): 96-110, 2020 07 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32589923
7.
Promotion of somatic CAG repeat expansion by Fan1 knock-out in Huntington's disease knock-in mice is blocked by Mlh1 knock-out.
Hum Mol Genet
; 29(18): 3044-3053, 2020 11 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32876667
8.
Population-specific genetic modification of Huntington's disease in Venezuela.
PLoS Genet
; 14(5): e1007274, 2018 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29750799
9.
Synthesis and evaluation of sulfonyl piperazine LpxH inhibitors.
Bioorg Chem
; 102: 104055, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32663666
10.
Recovery of hydrochloric acid using positively-charged nanofiltration membrane with selective acid permeability and acid resistance.
J Environ Manage
; 260: 110001, 2020 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31941640
11.
Novel allele-specific quantification methods reveal no effects of adult onset CAG repeats on HTT mRNA and protein levels.
Hum Mol Genet
; 26(7): 1258-1267, 2017 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28165127
12.
A modifier of Huntington's disease onset at the MLH1 locus.
Hum Mol Genet
; 26(19): 3859-3867, 2017 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28934397
13.
High resolution time-course mapping of early transcriptomic, molecular and cellular phenotypes in Huntington's disease CAG knock-in mice across multiple genetic backgrounds.
Hum Mol Genet
; 26(5): 913-922, 2017 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28334820
14.
The HTT CAG-Expansion Mutation Determines Age at Death but Not Disease Duration in Huntington Disease.
Am J Hum Genet
; 98(2): 287-98, 2016 Feb 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-26849111
15.
Full sequence of mutant huntingtin 3'-untranslated region and modulation of its gene regulatory activity by endogenous microRNA.
J Hum Genet
; 64(10): 995-1004, 2019 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-31296921
16.
Enhancing the Kinetic Stability and Lifetime of Organic Light-Emitting Diodes based on Bipolar Hosts by using Spiroconjugation.
Chemphyschem
; 19(14): 1711-1715, 2018 07 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-29719110
17.
Recovery of sulfuric acid aqueous solution from copper-refining sulfuric acid wastewater using nanofiltration membrane process.
J Environ Manage
; 223: 652-657, 2018 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29975892
18.
Hydrophilic and positively charged polyethylenimine-functionalized mesoporous magnetic clusters for highly efficient removal of Pb(II) and Cr(VI) from wastewater.
J Environ Manage
; 206: 740-748, 2018 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29161676
19.
Towards a Novel Class of Multitarget-Directed Ligands: Dual P2X7-NMDA Receptor Antagonists.
Molecules
; 23(1)2018 Jan 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-29361735
20.
Early and brain region-specific decrease of de novo cholesterol biosynthesis in Huntington's disease: A cross-validation study in Q175 knock-in mice.
Neurobiol Dis
; 98: 66-76, 2017 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-27913290