Detalhe da pesquisa
1.
RAS-MAPK-MSK1 pathway modulates ataxin 1 protein levels and toxicity in SCA1.
Nature
; 498(7454): 325-331, 2013 Jun 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-23719381
2.
Reduction of protein kinase A-mediated phosphorylation of ATXN1-S776 in Purkinje cells delays onset of Ataxia in a SCA1 mouse model.
Neurobiol Dis
; 116: 93-105, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29758256
3.
Mechanisms of tunneling nanotube-based propagation of neurodegenerative disease proteins.
Front Mol Neurosci
; 15: 957067, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35909452
4.
Degradation of Bone Quality in a Transgenic Mouse Model of Alzheimer's Disease.
J Bone Miner Res
; 37(12): 2548-2565, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36250342
5.
Intercellular Propagation and Aggregate Seeding of Mutant Ataxin-1.
J Mol Neurosci
; 72(4): 708-718, 2022 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-34826062
6.
Treating Neurodegenerative Disease with Antioxidants: Efficacy of the Bioactive Phenol Resveratrol and Mitochondrial-Targeted MitoQ and SkQ.
Antioxidants (Basel)
; 10(4)2021 Apr 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33917835
7.
Robust light-dark patterns and reduced amyloid load in an Alzheimer's disease transgenic mouse model.
Sci Rep
; 10(1): 11436, 2020 07 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32651420
8.
The effect of succinic acid on the metabolic profile in high-fat diet-induced obesity and insulin resistance.
Physiol Rep
; 8(21): e14630, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33185326
9.
Active c-jun N-terminal kinase induces caspase cleavage of tau and additional phosphorylation by GSK-3beta is required for tau aggregation.
Eur J Neurosci
; 27(11): 2897-906, 2008 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-18540881
10.
Treating SCA1 Mice with Water-Soluble Compounds to Non-Specifically Boost Mitochondrial Function.
J Vis Exp
; (119)2017 01 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-28190022
11.
Short-term succinic acid treatment mitigates cerebellar mitochondrial OXPHOS dysfunction, neurodegeneration and ataxia in a Purkinje-specific spinocerebellar ataxia type 1 (SCA1) mouse model.
PLoS One
; 12(12): e0188425, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-29211771
12.
Formation of phospho-SAPK/JNK granules in the hippocampus is an early event in Alzheimer disease.
J Neuropathol Exp Neurol
; 65(5): 455-64, 2006 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-16772869
13.
Expansion, mosaicism and interruption: mechanisms of the CAG repeat mutation in spinocerebellar ataxia type 1.
Cerebellum Ataxias
; 3: 20, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27895927
14.
Inhibition of ligand binding to G protein-coupled receptors by arachidonic acid.
J Mol Neurosci
; 27(2): 185-94, 2005.
Artigo
em Inglês
| MEDLINE | ID: mdl-16186629
15.
Stabilization and Degradation Mechanisms of Cytoplasmic Ataxin-1.
J Exp Neurosci
; 9(Suppl 2): 123-9, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-27168726
16.
Working memory and executive function decline across normal aging, mild cognitive impairment, and Alzheimer's disease.
Biomed Res Int
; 2015: 748212, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26550575
17.
Regulation of ataxin-1 phosphorylation and its impact on biology.
Methods Mol Biol
; 1010: 201-9, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23754227
18.
Staging of Alzheimer's pathology in triple transgenic mice: a light and electron microscopic analysis.
Int J Alzheimers Dis
; 20102010 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20798886
19.
Relation of hippocampal phospho-SAPK/JNK granules in Alzheimer's disease and tauopathies to granulovacuolar degeneration bodies.
Acta Neuropathol
; 113(1): 63-73, 2007 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-17089132
20.
Caspase cleavage of tau: linking amyloid and neurofibrillary tangles in Alzheimer's disease.
Proc Natl Acad Sci U S A
; 100(17): 10032-7, 2003 Aug 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-12888622