Detalhe da pesquisa
1.
Whole-genome analysis of noncoding genetic variations identifies multiscale regulatory element perturbations associated with Hirschsprung disease.
Genome Res
; 30(11): 1618-1632, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32948616
2.
Identification of Genes Associated With Hirschsprung Disease, Based on Whole-Genome Sequence Analysis, and Potential Effects on Enteric Nervous System Development.
Gastroenterology
; 155(6): 1908-1922.e5, 2018 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30217742
3.
Correction of Hirschsprung-Associated Mutations in Human Induced Pluripotent Stem Cells Via Clustered Regularly Interspaced Short Palindromic Repeats/Cas9, Restores Neural Crest Cell Function.
Gastroenterology
; 153(1): 139-153.e8, 2017 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28342760
4.
Identification of GLI Mutations in Patients With Hirschsprung Disease That Disrupt Enteric Nervous System Development in Mice.
Gastroenterology
; 149(7): 1837-1848.e5, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26261006
5.
Organoid cultures for cancer modeling.
Cell Stem Cell
; 30(7): 917-937, 2023 07 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37315564
6.
Organoid models of breathing disorders reveal patterning defect of hindbrain neurons caused by PHOX2B-PARMs.
Stem Cell Reports
; 18(7): 1500-1515, 2023 07 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37352849
7.
Transcriptomics of Hirschsprung disease patient-derived enteric neural crest cells reveals a role for oxidative phosphorylation.
Nat Commun
; 14(1): 2157, 2023 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37061531
8.
Ciliary protein Kif7 regulates Gli and Ezh2 for initiating the neuronal differentiation of enteric neural crest cells during development.
Sci Adv
; 7(42): eabf7472, 2021 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34644112