Detalhe da pesquisa
1.
Early Bactericidal Activity of Meropenem plus Clavulanate (with or without Rifampin) for Tuberculosis: The COMRADE Randomized, Phase 2A Clinical Trial.
Am J Respir Crit Care Med
; 205(10): 1228-1235, 2022 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35258443
2.
Glby, Encoded by MAB_3167c, Is Required for In Vivo Growth of Mycobacteroides abscessus and Exhibits Mild ß-Lactamase Activity.
J Bacteriol
; 204(5): e0004622, 2022 05 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-35380462
3.
Potency of Omadacycline against Mycobacteroides abscessus Clinical Isolates In Vitro and in a Mouse Model of Pulmonary Infection.
Antimicrob Agents Chemother
; 66(1): e0170421, 2022 01 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-34662184
4.
T405, a New Penem, Exhibits In Vivo Efficacy against M. abscessus and Synergy with ß-Lactams Imipenem and Cefditoren.
Antimicrob Agents Chemother
; 66(6): e0053622, 2022 06 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-35638855
5.
ß-Lactam Combinations That Exhibit Synergy against Mycobacteroides abscessus Clinical Isolates.
Antimicrob Agents Chemother
; 65(4)2021 03 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-33361310
6.
Synergistic Efficacy of ß-Lactam Combinations against Mycobacterium abscessus Pulmonary Infection in Mice.
Antimicrob Agents Chemother
; 63(8)2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31109979
7.
Select ß-Lactam Combinations Exhibit Synergy against Mycobacterium abscessus In Vitro.
Antimicrob Agents Chemother
; 63(4)2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30745389
8.
In Vitro Activity of the New ß-Lactamase Inhibitors Relebactam and Vaborbactam in Combination with ß-Lactams against Mycobacterium abscessus Complex Clinical Isolates.
Antimicrob Agents Chemother
; 63(3)2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30642943
9.
Inhibition of innate immune cytosolic surveillance by an M. tuberculosis phosphodiesterase.
Nat Chem Biol
; 13(2): 210-217, 2017 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-28106876
10.
Non-classical transpeptidases yield insight into new antibacterials.
Nat Chem Biol
; 13(1): 54-61, 2017 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-27820797
11.
The Driving Force for the Acylation of ß-Lactam Antibiotics by L,D-Transpeptidase 2: Quantum Mechanics/Molecular Mechanics (QM/MM) Study.
Chemphyschem
; 20(9): 1126-1134, 2019 05 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30969480
12.
Have we realized the full potential of ß-lactams for treating drug-resistant TB?
IUBMB Life
; 70(9): 881-888, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29934998
13.
Molecular insight on the non-covalent interactions between carbapenems and L,D-transpeptidase 2 from Mycobacterium tuberculosis: ONIOM study.
J Comput Aided Mol Des
; 32(6): 687-701, 2018 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29845435
14.
Mutation in an Unannotated Protein Confers Carbapenem Resistance in Mycobacterium tuberculosis.
Antimicrob Agents Chemother
; 61(3)2017 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-28069655
15.
Pyrazinoic Acid Inhibits a Bifunctional Enzyme in Mycobacterium tuberculosis.
Antimicrob Agents Chemother
; 61(7)2017 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28438933
16.
Mycobacterium abscessus l,d-Transpeptidases Are Susceptible to Inactivation by Carbapenems and Cephalosporins but Not Penicillins.
Antimicrob Agents Chemother
; 61(10)2017 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-28760902
17.
In vitro and in vivo activity of biapenem against drug-susceptible and rifampicin-resistant Mycobacterium tuberculosis.
J Antimicrob Chemother
; 72(8): 2320-2325, 2017 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28575382
18.
Structural insight into the inactivation of Mycobacterium tuberculosis non-classical transpeptidase LdtMt2 by biapenem and tebipenem.
BMC Biochem
; 18(1): 8, 2017 05 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-28545389
19.
Loss of a Functionally and Structurally Distinct ld-Transpeptidase, LdtMt5, Compromises Cell Wall Integrity in Mycobacterium tuberculosis.
J Biol Chem
; 290(42): 25670-85, 2015 Oct 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-26304120
20.
Role of the Cys154Arg Substitution in Ribosomal Protein L3 in Oxazolidinone Resistance in Mycobacterium tuberculosis.
Antimicrob Agents Chemother
; 60(5): 3202-6, 2016 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-26953211