Detalhe da pesquisa
1.
Lineage regulators direct BMP and Wnt pathways to cell-specific programs during differentiation and regeneration.
Cell
; 147(3): 577-89, 2011 Oct 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-22036566
2.
Densely interconnected transcriptional circuits control cell states in human hematopoiesis.
Cell
; 144(2): 296-309, 2011 Jan 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-21241896
3.
ARID5B as a critical downstream target of the TAL1 complex that activates the oncogenic transcriptional program and promotes T-cell leukemogenesis.
Genes Dev
; 31(23-24): 2343-2360, 2017 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29326336
4.
A genome-scale in vivo loss-of-function screen identifies Phf6 as a lineage-specific regulator of leukemia cell growth.
Genes Dev
; 29(5): 483-8, 2015 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25737277
5.
Targeted inhibition of PI3Kα/δ is synergistic with BCL-2 blockade in genetically defined subtypes of DLBCL.
Blood
; 133(1): 70-80, 2019 01 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30322870
6.
CXCR4 upregulation is an indicator of sensitivity to B-cell receptor/PI3K blockade and a potential resistance mechanism in B-cell receptor-dependent diffuse large B-cell lymphomas.
Haematologica
; 105(5): 1361-1368, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-31471373
7.
DTX3L E3 ligase targets p53 for degradation at poly ADP-ribose polymerase-associated DNA damage sites.
iScience
; 26(4): 106444, 2023 Apr 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-37096048
8.
Discovery of CC-90011: A Potent and Selective Reversible Inhibitor of Lysine Specific Demethylase 1 (LSD1).
J Med Chem
; 63(23): 14522-14529, 2020 12 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33034194
9.
A peripheral immune signature of responsiveness to PD-1 blockade in patients with classical Hodgkin lymphoma.
Nat Med
; 26(9): 1468-1479, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32778827
10.
ASCL1 is a MYCN- and LMO1-dependent member of the adrenergic neuroblastoma core regulatory circuitry.
Nat Commun
; 10(1): 5622, 2019 12 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31819055
11.
Genomic analyses of flow-sorted Hodgkin Reed-Sternberg cells reveal complementary mechanisms of immune evasion.
Blood Adv
; 3(23): 4065-4080, 2019 12 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31816062
12.
The TAL1 complex targets the FBXW7 tumor suppressor by activating miR-223 in human T cell acute lymphoblastic leukemia.
J Exp Med
; 210(8): 1545-57, 2013 Jul 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-23857984
13.
Core transcriptional regulatory circuit controlled by the TAL1 complex in human T cell acute lymphoblastic leukemia.
Cancer Cell
; 22(2): 209-21, 2012 Aug 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-22897851
14.
Genome-wide maps of histone modifications unwind in vivo chromatin states of the hair follicle lineage.
Cell Stem Cell
; 9(3): 219-32, 2011 Sep 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-21885018
15.
The role of the chromatin remodeler Mi-2beta in hematopoietic stem cell self-renewal and multilineage differentiation.
Genes Dev
; 22(9): 1174-89, 2008 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18451107
16.
Aberrant chromatin at genes encoding stem cell regulators in human mixed-lineage leukemia.
Genes Dev
; 22(24): 3403-8, 2008 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19141473