Detalhe da pesquisa
1.
Cooperative sensing of mitochondrial DNA by ZBP1 and cGAS promotes cardiotoxicity.
Cell
; 186(14): 3013-3032.e22, 2023 07 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37352855
2.
Mitochondrial DNA release and sensing in innate immune responses.
Hum Mol Genet
; 33(R1): R80-R91, 2024 May 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-38779772
3.
The molecular basis of tight nuclear tethering and inactivation of cGAS.
Nature
; 587(7835): 673-677, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32911481
4.
Activation of the cGAS-STING innate immune response in cells with deficient mitochondrial topoisomerase TOP1MT.
Hum Mol Genet
; 32(15): 2422-2440, 2023 07 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-37129502
5.
A conserved PLPLRT/SD motif of STING mediates the recruitment and activation of TBK1.
Nature
; 569(7758): 718-722, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-31118511
6.
Inflammatory and interferon gene expression signatures in patients with mitochondrial disease.
J Transl Med
; 21(1): 331, 2023 05 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-37208779
7.
Loss of Mitochondrial Protease CLPP Activates Type I IFN Responses through the Mitochondrial DNA-cGAS-STING Signaling Axis.
J Immunol
; 206(8): 1890-1900, 2021 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33731338
8.
Loss of mitochondrial ClpP, Lonp1, and Tfam triggers transcriptional induction of Rnf213, a susceptibility factor for moyamoya disease.
Neurogenetics
; 21(3): 187-203, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32342250
9.
Inhibition of SIRT1/2 upregulates HSPA5 acetylation and induces pro-survival autophagy via ATF4-DDIT4-mTORC1 axis in human lung cancer cells.
Apoptosis
; 24(9-10): 798-811, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31321634
10.
DDIT3 and KAT2A Proteins Regulate TNFRSF10A and TNFRSF10B Expression in Endoplasmic Reticulum Stress-mediated Apoptosis in Human Lung Cancer Cells.
J Biol Chem
; 290(17): 11108-18, 2015 Apr 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-25770212
11.
3D convolutional neural networks predict cellular metabolic pathway use from fluorescence lifetime decay data.
APL Bioeng
; 8(1): 016112, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38420625
12.
Caspase-11 drives macrophage hyperinflammation in models of Polg-related mitochondrial disease.
bioRxiv
; 2024 May 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-38798587
13.
Inflammatory and interferon gene expression signatures in patients with mitochondrial disease.
Res Sq
; 2023 Feb 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-36909538
14.
Assessing Mitochondrial DNA Release into the Cytosol and Subsequent Activation of Innate Immune-related Pathways in Mammalian Cells.
Curr Protoc
; 2(2): e372, 2022 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-35175686
15.
Age-Dependent Decline in Neuron Growth Potential and Mitochondria Functions in Cortical Neurons.
Cells
; 10(7)2021 06 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-34209640
16.
Elevated type I interferon responses potentiate metabolic dysfunction, inflammation, and accelerated aging in mtDNA mutator mice.
Sci Adv
; 7(22)2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-34039599