Detalhe da pesquisa
1.
Glutamate transporter EAAT2: regulation, function, and potential as a therapeutic target for neurological and psychiatric disease.
Cell Mol Life Sci
; 72(18): 3489-506, 2015 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-26033496
2.
Impact of a pyridazine derivative on tripartite synapse ultrastructure in hippocampus: a three-dimensional analysis.
Front Cell Neurosci
; 17: 1229731, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37671169
3.
Increased glial glutamate transporter EAAT2 expression reduces epileptogenic processes following pilocarpine-induced status epilepticus.
Neurobiol Dis
; 47(2): 145-54, 2012 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-22513140
4.
Structure-activity relationship study of pyridazine derivatives as glutamate transporter EAAT2 activators.
Bioorg Med Chem Lett
; 21(19): 5774-7, 2011 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21875806
5.
Oxidative damage to RNA: mechanisms, consequences, and diseases.
Cell Mol Life Sci
; 67(11): 1817-29, 2010 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-20148281
6.
Emerging role of glutamate in the pathophysiology and therapeutics of Gulf War illness.
Life Sci
; 280: 119609, 2021 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33991547
7.
Effects of axon degeneration on oligodendrocyte lineage cells: dorsal rhizotomy evokes a repair response while axon degeneration rostral to spinal contusion induces both repair and apoptosis.
Glia
; 58(11): 1304-19, 2010 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20607865
8.
Restoring tripartite glutamatergic synapses: A potential therapy for mood and cognitive deficits in Gulf War illness.
Neurobiol Stress
; 13: 100240, 2020 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-33344696
9.
A novel noncoding RNA rescues mutant SOD1-mediated cell death.
FASEB J
; 22(3): 691-702, 2008 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-17957031
10.
Enhancement of tripartite synapses as a potential therapeutic strategy for Alzheimer's disease: a preclinical study in rTg4510 mice.
Alzheimers Res Ther
; 11(1): 75, 2019 08 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-31439023
11.
Messenger RNA oxidation is an early event preceding cell death and causes reduced protein expression.
FASEB J
; 21(11): 2753-64, 2007 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-17496160
12.
Pyridazine-derivatives Enhance Structural and Functional Plasticity of Tripartite Synapse Via Activation of Local Translation in Astrocytic Processes.
Neuroscience
; 388: 224-238, 2018 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30056115
13.
The identification and characterization of oxidized RNAs in Alzheimer's disease.
J Neurosci
; 23(12): 4913-21, 2003 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-12832513
14.
Restored glial glutamate transporter EAAT2 function as a potential therapeutic approach for Alzheimer's disease.
J Exp Med
; 212(3): 319-32, 2015 Mar 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-25711212
15.
Molecular cloning, gene structure, expression profile and functional characterization of the mouse glutamate transporter (EAAT3) interacting protein GTRAP3-18.
Gene
; 292(1-2): 81-90, 2002 Jun 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-12119102
16.
Small-molecule activator of glutamate transporter EAAT2 translation provides neuroprotection.
J Clin Invest
; 124(3): 1255-67, 2014 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-24569372
17.
Glutamate transporter EAAT2: a new target for the treatment of neurodegenerative diseases.
Future Med Chem
; 4(13): 1689-700, 2012 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-22924507
18.
Identification of translational activators of glial glutamate transporter EAAT2 through cell-based high-throughput screening: an approach to prevent excitotoxicity.
J Biomol Screen
; 15(6): 653-62, 2010 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-20508255
19.
Increased glial glutamate transporter EAAT2 expression reduces visceral nociceptive response in mice.
Am J Physiol Gastrointest Liver Physiol
; 296(1): G129-34, 2009 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-19023027
20.
RNA oxidation: a contributing factor or an epiphenomenon in the process of neurodegeneration.
Free Radic Res
; 42(9): 773-7, 2008 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-18661427