Detalhe da pesquisa
1.
The ERK5/NF-κB signaling pathway targets endometrial cancer proliferation and survival.
Cell Mol Life Sci
; 79(10): 524, 2022 Sep 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-36123565
2.
Discovery of a selective inhibitor of doublecortin like kinase 1.
Nat Chem Biol
; 16(6): 635-643, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32251410
3.
An ERK5-KLF2 signalling module regulates early embryonic gene expression and telomere rejuvenation in stem cells.
Biochem J
; 478(23): 4119-4136, 2021 12 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34780645
4.
Methuosis Contributes to Jaspine-B-Induced Cell Death.
Int J Mol Sci
; 23(13)2022 Jun 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-35806262
5.
The novel proautophagy anticancer drug ABTL0812 potentiates chemotherapy in adenocarcinoma and squamous nonsmall cell lung cancer.
Int J Cancer
; 147(4): 1163-1179, 2020 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31943158
6.
SUMOylation Is Required for ERK5 Nuclear Translocation and ERK5-Mediated Cancer Cell Proliferation.
Int J Mol Sci
; 21(6)2020 Mar 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-32209980
7.
TRIB3 silencing promotes the downregulation of Akt pathway and PAX3-FOXO1 in high-risk rhabdomyosarcoma.
Exp Hematol Oncol
; 13(1): 38, 2024 Apr 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-38581035
8.
Brain specific kinase-1 BRSK1/SAD-B associates with lipid rafts: modulation of kinase activity by lipid environment.
Biochim Biophys Acta
; 1811(12): 1124-35, 2011 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-22020259
9.
ERK5 Inhibition Induces Autophagy-Mediated Cancer Cell Death by Activating ER Stress.
Front Cell Dev Biol
; 9: 742049, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34805151
10.
The anti-cancer drug ABTL0812 induces ER stress-mediated cytotoxic autophagy by increasing dihydroceramide levels in cancer cells.
Autophagy
; 17(6): 1349-1366, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32397857
11.
The antitumour drug ABTL0812 impairs neuroblastoma growth through endoplasmic reticulum stress-mediated autophagy and apoptosis.
Cell Death Dis
; 11(9): 773, 2020 09 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-32943619
12.
STK11 (LKB1) missense somatic mutant isoforms promote tumor growth, motility and inflammation.
Commun Biol
; 3(1): 366, 2020 07 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32647375
13.
Genetic manipulation of LKB1 elicits lethal metastatic prostate cancer.
J Exp Med
; 217(6)2020 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32219437
14.
Neuronal Growth Factor regulates Brain Specific Kinase 1 expression by inhibiting promoter methylation and promoting Sp1 recruitment.
Neurochem Int
; 120: 213-223, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30196145
15.
Structural and Atropisomeric Factors Governing the Selectivity of Pyrimido-benzodiazipinones as Inhibitors of Kinases and Bromodomains.
ACS Chem Biol
; 13(9): 2438-2448, 2018 09 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-30102854
16.
ERK5 and Cell Proliferation: Nuclear Localization Is What Matters.
Front Cell Dev Biol
; 4: 105, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27713878
17.
Mutation of the 3-Phosphoinositide-Dependent Protein Kinase 1 (PDK1) Substrate-Docking Site in the Developing Brain Causes Microcephaly with Abnormal Brain Morphogenesis Independently of Akt, Leading to Impaired Cognition and Disruptive Behaviors.
Mol Cell Biol
; 36(23): 2967-2982, 2016 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27644329
18.
The New Antitumor Drug ABTL0812 Inhibits the Akt/mTORC1 Axis by Upregulating Tribbles-3 Pseudokinase.
Clin Cancer Res
; 22(10): 2508-19, 2016 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26671995
19.
Identification of the sucrose non-fermenting related kinase SNRK, as a novel LKB1 substrate.
FEBS Lett
; 579(6): 1417-23, 2005 Feb 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-15733851
20.
Insulin-induced Drosophila S6 kinase activation requires phosphoinositide 3-kinase and protein kinase B.
Biochem J
; 374(Pt 2): 297-306, 2003 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-12841848