Detalhe da pesquisa
1.
Abnormal polyamine metabolism is unique to the neuropathic forms of MPS: potential for biomarker development and insight into pathogenesis.
Hum Mol Genet
; 26(19): 3837-3849, 2017 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28934395
2.
Neuroinflammatory targets and treatments for epilepsy validated in experimental models.
Epilepsia
; 58 Suppl 3: 27-38, 2017 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28675563
3.
Liver-directed gene therapy corrects cardiovascular lesions in feline mucopolysaccharidosis type I.
Proc Natl Acad Sci U S A
; 111(41): 14894-9, 2014 Oct 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-25267637
4.
Neonatal tolerance induction enables accurate evaluation of gene therapy for MPS I in a canine model.
Mol Genet Metab
; 119(1-2): 124-30, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27386755
5.
Neonatal Systemic AAV Induces Tolerance to CNS Gene Therapy in MPS I Dogs and Nonhuman Primates.
Mol Ther
; 23(8): 1298-1307, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-26022732
6.
Intrathecal gene therapy corrects CNS pathology in a feline model of mucopolysaccharidosis I.
Mol Ther
; 22(12): 2018-2027, 2014 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-25027660
7.
Efficient CNS gene delivery by intravenous injection.
Nat Methods
; 7(11): 905-7, 2010 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-20953176
8.
HIV-1 Tat neurotoxicity: a model of acute and chronic exposure, and neuroprotection by gene delivery of antioxidant enzymes.
Neurobiol Dis
; 45(2): 657-70, 2012 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-22036626
9.
Role of CCR5 and its ligands in the control of vascular inflammation and leukocyte recruitment required for acute excitotoxic seizure induction and neural damage.
FASEB J
; 25(2): 737-53, 2011 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-20940264
10.
Blood-brain barrier abnormalities caused by HIV-1 gp120: mechanistic and therapeutic implications.
ScientificWorldJournal
; 2012: 482575, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22448134
11.
HIV-1 gp120 upregulates matrix metalloproteinases and their inhibitors in a rat model of HIV encephalopathy.
Eur J Neurosci
; 34(12): 2015-23, 2011 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-22092673
12.
Blood-brain barrier abnormalities caused by exposure to HIV-1 gp120--protection by gene delivery of antioxidant enzymes.
Neurobiol Dis
; 38(2): 313-25, 2010 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-20219678
13.
Gene transfer to the cerebellum.
Cerebellum
; 9(4): 587-97, 2010 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-20700772
14.
A rat model of human immunodeficiency virus 1 encephalopathy using envelope glycoprotein gp120 expression delivered by SV40 vectors.
J Neuropathol Exp Neurol
; 68(5): 456-73, 2009 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-19525894
15.
HIV-1 gp120 neurotoxicity proximally and at a distance from the point of exposure: protection by rSV40 delivery of antioxidant enzymes.
Neurobiol Dis
; 34(3): 462-76, 2009 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-19327399
16.
Safe and Sustained Expression of Human Iduronidase After Intrathecal Administration of Adeno-Associated Virus Serotype 9 in Infant Rhesus Monkeys.
Hum Gene Ther
; 30(8): 957-966, 2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31017018
17.
Evaluation of Intrathecal Routes of Administration for Adeno-Associated Viral Vectors in Large Animals.
Hum Gene Ther
; 29(1): 15-24, 2018 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28806897
18.
The p38 mitogen-activated protein kinase signaling pathway is coupled to Toll-like receptor 5 to mediate gene regulation in response to Pseudomonas aeruginosa infection in human airway epithelial cells.
Infect Immun
; 75(12): 5985-92, 2007 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-17908812
19.
Preterminal host dendritic cells in irradiated mice prime CD8+ T cell-mediated acute graft-versus-host disease.
J Clin Invest
; 109(10): 1335-44, 2002 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-12021249
20.
Long-term gene expression in dividing and nondividing cells using SV40-derived vectors.
Mol Biotechnol
; 34(2): 257-70, 2006 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-17172671