Detalhe da pesquisa
1.
Effects of N-glycan modifications on spike expression, virus infectivity, and neutralization sensitivity in ancestral compared to Omicron SARS-CoV-2 variants.
PLoS Pathog
; 19(11): e1011788, 2023 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-37943965
2.
Second-site suppressor mutations reveal connection between the drug-binding pocket and nucleotide-binding domain 1 of human P-glycoprotein (ABCB1).
Drug Resist Updat
; 71: 101009, 2023 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-37797431
3.
Key Substitutions in the Spike Protein of SARS-CoV-2 Variants Can Predict Resistance to Monoclonal Antibodies, but Other Substitutions Can Modify the Effects.
J Virol
; 96(1): e0111021, 2022 01 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34668774
4.
Characterization of Entry Pathways, Species-Specific Angiotensin-Converting Enzyme 2 Residues Determining Entry, and Antibody Neutralization Evasion of Omicron BA.1, BA.1.1, BA.2, and BA.3 Variants.
J Virol
; 96(17): e0114022, 2022 09 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-36000843
5.
Reversing the direction of drug transport mediated by the human multidrug transporter P-glycoprotein.
Proc Natl Acad Sci U S A
; 117(47): 29609-29617, 2020 11 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-33168729
6.
Overexpression of Human ABCB1 and ABCG2 Reduces the Susceptibility of Cancer Cells to the Histone Deacetylase 6-Specific Inhibitor Citarinostat.
Int J Mol Sci
; 22(5)2021 Mar 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33807514
7.
Licochalcone A Selectively Resensitizes ABCG2-Overexpressing Multidrug-Resistant Cancer Cells to Chemotherapeutic Drugs.
J Nat Prod
; 83(5): 1461-1472, 2020 05 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-32347726
8.
ATP-dependent thermostabilization of human P-glycoprotein (ABCB1) is blocked by modulators.
Biochem J
; 476(24): 3737-3750, 2019 12 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-31774117
9.
A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein.
Mol Pharmacol
; 96(5): 629-640, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31515284
10.
Synthesis and Characterization of Bodipy-FL-Cyclosporine A as a Substrate for Multidrug Resistance-Linked P-Glycoprotein (ABCB1).
Drug Metab Dispos
; 47(10): 1013-1023, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31371421
11.
Avapritinib: A Selective Inhibitor of KIT and PDGFRα that Reverses ABCB1 and ABCG2-Mediated Multidrug Resistance in Cancer Cell Lines.
Mol Pharm
; 16(7): 3040-3052, 2019 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31117741
12.
Large-scale purification of functional human P-glycoprotein (ABCB1).
Protein Expr Purif
; 159: 60-68, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30851394
13.
The Selective Class IIa Histone Deacetylase Inhibitor TMP195 Resensitizes ABCB1- and ABCG2-Overexpressing Multidrug-Resistant Cancer Cells to Cytotoxic Anticancer Drugs.
Int J Mol Sci
; 21(1)2019 Dec 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-31905792
14.
Targeted Isolation of Antibodies Directed against Major Sites of SIV Env Vulnerability.
PLoS Pathog
; 12(4): e1005537, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-27064278
15.
Correction: Targeted Isolation of Antibodies Directed against Major Sites of SIV Env Vulnerability.
PLoS Pathog
; 12(5): e1005674, 2016 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-27219002
16.
PBK/TOPK inhibitor OTS964 resistance is mediated by ABCB1-dependent transport function in cancer: in vitro and in vivo study.
Mol Cancer
; 21(1): 40, 2022 02 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35135547
17.
Design and synthesis of small molecule-sulfotyrosine mimetics that inhibit HIV-1 entry.
Bioorg Med Chem
; 24(8): 1718-28, 2016 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26968647
18.
Retrotransposon Ty1 RNA contains a 5'-terminal long-range pseudoknot required for efficient reverse transcription.
RNA
; 19(3): 320-32, 2013 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-23329695
19.
The HIV-2 Rev-response element: determining secondary structure and defining folding intermediates.
Nucleic Acids Res
; 41(13): 6637-49, 2013 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-23640333
20.
Exploring Ty1 retrotransposon RNA structure within virus-like particles.
Nucleic Acids Res
; 41(1): 463-73, 2013 Jan 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-23093595