Detalhe da pesquisa
1.
First-in-human study of alpibectir (BVL-GSK098), a novel potent anti-TB drug.
J Antimicrob Chemother
; 2024 Apr 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-38656557
2.
Preclinical candidate for the treatment of visceral leishmaniasis that acts through proteasome inhibition.
Proc Natl Acad Sci U S A
; 116(19): 9318-9323, 2019 05 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30962368
3.
An Uncharacterized Member of the Gls24 Protein Superfamily Is a Putative Sensor of Essential Amino Acid Availability in Streptococcus pneumoniae.
Microb Ecol
; 77(2): 471-487, 2019 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-29978356
4.
Chemical genetics of Plasmodium falciparum.
Nature
; 465(7296): 311-5, 2010 May 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-20485428
5.
Antimicrobial activity of hydroxytyrosol: a current controversy.
Biosci Biotechnol Biochem
; 80(4): 801-10, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-26679750
6.
CD8 T cells are dispensable for experimental autoimmune prostatitis induction and chronic pelvic pain development.
Front Immunol
; 15: 1387142, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38807587
7.
Expression of HPV-16 E6 and E7 oncoproteins alters Chlamydia trachomatis developmental cycle and induces increased levels of immune regulatory molecules.
Front Cell Infect Microbiol
; 13: 1214017, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37743859
8.
Short-course combination treatment for experimental chronic Chagas disease.
Sci Transl Med
; 15(726): eadg8105, 2023 12 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-38091410
9.
DNDI-6174 is a preclinical candidate for visceral leishmaniasis that targets the cytochrome bc1.
Sci Transl Med
; 15(726): eadh9902, 2023 12 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-38091406
10.
Identification of ß-Lactams Active against Mycobacterium tuberculosis by a Consortium of Pharmaceutical Companies and Academic Institutions.
ACS Infect Dis
; 8(3): 557-573, 2022 03 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-35192346
11.
The small-molecule SMARt751 reverses Mycobacterium tuberculosis resistance to ethionamide in acute and chronic mouse models of tuberculosis.
Sci Transl Med
; 14(643): eaaz6280, 2022 05 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35507672
12.
Immunization with SP_1992 (DiiA) Protein of Streptococcus pneumoniae Reduces Nasopharyngeal Colonization and Protects against Invasive Disease in Mice.
Vaccines (Basel)
; 9(3)2021 Feb 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-33668195
13.
A novel class of fast-acting antimalarial agents: Substituted 15-membered azalides.
Br J Pharmacol
; 178(2): 363-377, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33085774
14.
Evaluation of a class of isatinoids identified from a high-throughput screen of human kinase inhibitors as anti-Sleeping Sickness agents.
PLoS Negl Trop Dis
; 13(2): e0007129, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30735501
15.
Remission of type 2 diabetes mellitus after bariatric surgery - comparison between procedures.
Endokrynol Pol
; 68(1): 18-25, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28255977
16.
Hundreds of dual-stage antimalarial molecules discovered by a functional gametocyte screen.
Nat Commun
; 8: 15160, 2017 05 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-28513586
17.
The Discovery of Novel Antimalarial Aminoxadiazoles as a Promising Nonendoperoxide Scaffold.
J Med Chem
; 60(16): 6880-6896, 2017 08 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-28806082
18.
DiiA is a novel dimorphic cell wall protein of Streptococcus pneumoniae involved in invasive disease.
J Infect
; 73(1): 71-81, 2016 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27105656
19.
Hit-to-Lead Optimization of a Novel Class of Potent, Broad-Spectrum Trypanosomacides.
J Med Chem
; 59(21): 9686-9720, 2016 11 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27548560
20.
Carbamoyl Triazoles, Known Serine Protease Inhibitors, Are a Potent New Class of Antimalarials.
J Med Chem
; 58(16): 6448-55, 2015 Aug 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-26222445