Detalhe da pesquisa
1.
Enhancement of the Oral Availability of Cabazitaxel Using the Cytochrome P450 3A (CYP3A) Inhibitor Ritonavir in Mice.
Mol Pharm
; 20(5): 2477-2489, 2023 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36976574
2.
Organic anion-transporting polypeptide 2B1 knockout and humanized mice; insights into the handling of bilirubin and drugs.
Pharmacol Res
; 190: 106724, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36907287
3.
ABCB1 limits brain exposure of the KRASG12C inhibitor sotorasib, whereas ABCB1, CYP3A, and possibly OATP1a/1b restrict its oral availability.
Pharmacol Res
; 178: 106137, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35192958
4.
Coadministration of ABCB1/P-glycoprotein inhibitor elacridar improves tissue distribution of ritonavir-boosted oral cabazitaxel in mice.
Int J Pharm
; 650: 123708, 2024 Jan 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-38135258
5.
Interplay of OATP1A/1B/2B1 uptake transporters and ABCB1 and ABCG2 efflux transporters in the handling of bilirubin and drugs.
Biomed Pharmacother
; 175: 116644, 2024 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-38692057
6.
ABCB1 and ABCG2 Restrict Brain and Testis Accumulation and, Alongside CYP3A, Limit Oral Availability of the Novel TRK Inhibitor Selitrectinib.
Mol Cancer Ther
; 20(6): 1173-1182, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33785654
7.
The Neuroprotective Action of Amidated-Kyotorphin on Amyloid ß Peptide-Induced Alzheimer's Disease Pathophysiology.
Front Pharmacol
; 11: 985, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32733240