Detalhe da pesquisa
1.
An adjuvant strategy enabled by modulation of the physical properties of microbial ligands expands antigen immunogenicity.
Cell
; 185(4): 614-629.e21, 2022 02 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-35148840
2.
SARS-CoV-2 ORF8 modulates lung inflammation and clinical disease progression.
PLoS Pathog
; 20(5): e1011669, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38781259
3.
SARS-CoV-2 variant spike and accessory gene mutations alter pathogenesis.
Proc Natl Acad Sci U S A
; 119(37): e2204717119, 2022 09 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-36040867
4.
Diet-induced obesity and diabetes enhance mortality and reduce vaccine efficacy for SARS-CoV-2.
J Virol
; 97(11): e0133623, 2023 Nov 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-37846985
5.
Reduced SARS-CoV-2 mRNA vaccine immunogenicity and protection in mice with diet-induced obesity and insulin resistance.
J Allergy Clin Immunol
; 152(5): 1107-1120.e6, 2023 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37595760
6.
Phase 1-2 Trial of a SARS-CoV-2 Recombinant Spike Protein Nanoparticle Vaccine.
N Engl J Med
; 383(24): 2320-2332, 2020 12 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32877576
7.
The SKI complex is a broad-spectrum, host-directed antiviral drug target for coronaviruses, influenza, and filoviruses.
Proc Natl Acad Sci U S A
; 117(48): 30687-30698, 2020 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33184176
8.
Diet Induced Obesity and Diabetes Enhance Mortality and Reduces Vaccine Efficacy for SARS-CoV-2.
bioRxiv
; 2023 May 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36299426
9.
SARS-CoV-2 ORF6 protein does not antagonize interferon signaling in respiratory epithelial Calu-3 cells during infection.
mBio
; 14(4): e0119423, 2023 08 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-37377442
10.
Immunogenicity and protection of a variant nanoparticle vaccine that confers broad neutralization against SARS-CoV-2 variants.
Nat Commun
; 14(1): 1130, 2023 02 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-36854666
11.
A neonatal mouse model characterizes transmissibility of SARS-CoV-2 variants and reveals a role for ORF8.
bioRxiv
; 2023 Mar 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-36238716
12.
A neonatal mouse model characterizes transmissibility of SARS-CoV-2 variants and reveals a role for ORF8.
Nat Commun
; 14(1): 3026, 2023 05 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-37230979
13.
Carbohydrate fatty acid monosulphate: oil-in-water adjuvant enhances SARS-CoV-2 RBD nanoparticle-induced immunogenicity and protection in mice.
NPJ Vaccines
; 8(1): 18, 2023 Feb 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-36788219
14.
Host Cell Glycocalyx Remodeling Reveals SARS-CoV-2 Spike Protein Glycomic Binding Sites.
Front Mol Biosci
; 9: 799703, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35372520
15.
Reduced SARS-CoV-2 mRNA vaccine immunogenicity and protection in mice with diet-induced obesity and insulin resistance.
bioRxiv
; 2022 Dec 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-36523401
16.
PIKfyve-specific inhibitors restrict replication of multiple coronaviruses in vitro but not in a murine model of COVID-19.
Commun Biol
; 5(1): 808, 2022 08 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35962188
17.
Self-assembling short immunostimulatory duplex RNAs with broad-spectrum antiviral activity.
Mol Ther Nucleic Acids
; 29: 923-940, 2022 Sep 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-36032397
18.
mRNA booster vaccination protects aged mice against the SARS-CoV-2 Omicron variant.
Commun Biol
; 5(1): 790, 2022 08 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35933439
19.
The mRNA vaccine BNT162b2 demonstrates impaired TH1 immunogenicity in human elders in vitro and aged mice in vivo.
Res Sq
; 2022 Dec 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-36597547
20.
An aluminum hydroxide:CpG adjuvant enhances protection elicited by a SARS-CoV-2 receptor binding domain vaccine in aged mice.
Sci Transl Med
; 14(629): eabj5305, 2022 Jan 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-34783582