Detalhe da pesquisa
1.
Nonclinical safety assessment of recombinant human acid sphingomyelinase (rhASM) for the treatment of acid sphingomyelinase deficiency:the utility of animal models of disease in the toxicological evaluation of potential therapeutics.
Mol Genet Metab
; 114(2): 217-25, 2015 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-25092414
2.
Site-specific PEGylation of human thyroid stimulating hormone to prolong duration of action.
Bioconjug Chem
; 24(3): 408-18, 2013 Mar 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-23350694
3.
Identification and quantitation of Vesivirus 2117 particles in bioreactor fluids from infected Chinese hamster ovary cell cultures.
Biotechnol Bioeng
; 110(5): 1342-53, 2013 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-23184768
4.
Blockade of TGF-beta enhances tumor vaccine efficacy mediated by CD8(+) T cells.
Int J Cancer
; 126(7): 1666-74, 2010 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19830696
5.
Inhibition of glycogen biosynthesis via mTORC1 suppression as an adjunct therapy for Pompe disease.
Mol Genet Metab
; 100(4): 309-15, 2010 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-20554235
6.
Pulmonary delivery of recombinant acid sphingomyelinase improves clearance of lysosomal sphingomyelin from the lungs of a murine model of Niemann-Pick disease.
Mol Genet Metab
; 97(1): 35-42, 2009 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-19231265
7.
Thyroid-stimulating hormone restores bone volume, microarchitecture, and strength in aged ovariectomized rats.
J Bone Miner Res
; 22(6): 849-59, 2007 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-17352644
8.
Effective chemoimmunotherapy with anti-TGFß antibody and cyclophosphamide in a mouse model of breast cancer.
PLoS One
; 9(1): e85398, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24416401
9.
Carbohydrate-mediated polyethylene glycol conjugation of TSH improves its pharmacological properties.
Endocrinology
; 154(3): 1373-83, 2013 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-23389953
10.
Immunological effects of the TGFß-blocking antibody GC1008 in malignant pleural mesothelioma patients.
Oncoimmunology
; 2(8): e26218, 2013 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24179709
11.
Antibody targeting of TGF-ß in cancer patients.
Curr Pharm Biotechnol
; 12(12): 2176-89, 2011 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-21619535
12.
Synergistic enhancement of CD8+ T cell-mediated tumor vaccine efficacy by an anti-transforming growth factor-beta monoclonal antibody.
Clin Cancer Res
; 15(21): 6560-9, 2009 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19861451
13.
Newly reported roles of thyroid-stimulating hormone and follicle-stimulating hormone in bone remodelling.
Int Orthop
; 31(6): 753-7, 2007 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-17611756
14.
Transforming growth factor-beta2 (TGF-beta2) reverses the inhibitory effects of fibrin sealant on cutaneous wound repair in the pig.
Wound Repair Regen
; 10(4): 252-8, 2002.
Artigo
em Inglês
| MEDLINE | ID: mdl-12191008
15.
Characterization of proliferating human skeletal muscle-derived cells in vitro: differential modulation of myoblast markers by TGF-beta2.
J Cell Physiol
; 196(1): 70-8, 2003 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-12767042
16.
A biochemical and pharmacological comparison of enzyme replacement therapies for the glycolipid storage disorder Fabry disease.
Glycobiology
; 13(4): 305-13, 2003 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-12626384
17.
Pseudoseptic reactions to Hylan viscosupplementation: diagnosis and treatment.
Clin Orthop Relat Res
; (429): 349-50; author reply 350-1, 2004 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-15577509