Detalhe da pesquisa
1.
The gut microbiome switches mutant p53 from tumour-suppressive to oncogenic.
Nature
; 586(7827): 133-138, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32728212
2.
Residual apoptotic activity of a tumorigenic p53 mutant improves cancer therapy responses.
EMBO J
; 38(20): e102096, 2019 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31483066
3.
Monitoring autochthonous lung tumors induced by somatic CRISPR gene editing in mice using a secreted luciferase.
Mol Cancer
; 21(1): 191, 2022 10 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36192757
4.
Loss of p53 function at late stages of tumorigenesis confers ARF-dependent vulnerability to p53 reactivation therapy.
Proc Natl Acad Sci U S A
; 116(44): 22288-22293, 2019 10 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-31611375
5.
Transcriptome profiling and protease inhibition experiments identify proteases that activate H3N2 influenza A and influenza B viruses in murine airways.
J Biol Chem
; 295(33): 11388-11407, 2020 08 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-32303635
6.
Choice of binding sites for CTCFL compared to CTCF is driven by chromatin and by sequence preference.
Nucleic Acids Res
; 46(14): 7097-7107, 2018 08 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-29860503
7.
CK1α ablation in keratinocytes induces p53-dependent, sunburn-protective skin hyperpigmentation.
Proc Natl Acad Sci U S A
; 114(38): E8035-E8044, 2017 09 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-28878021
8.
Miz1 Controls Schwann Cell Proliferation via H3K36me2 Demethylase Kdm8 to Prevent Peripheral Nerve Demyelination.
J Neurosci
; 38(4): 858-877, 2018 01 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-29217679
9.
Antithetical NFATc1-Sox2 and p53-miR200 signaling networks govern pancreatic cancer cell plasticity.
EMBO J
; 34(4): 517-30, 2015 Feb 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-25586376
10.
Mutant p53 promotes tumor progression and metastasis by the endoplasmic reticulum UDPase ENTPD5.
Proc Natl Acad Sci U S A
; 113(52): E8433-E8442, 2016 12 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-27956623
11.
CRISPR-Cas9-based target validation for p53-reactivating model compounds.
Nat Chem Biol
; 12(1): 22-8, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-26595461
12.
ΔNp63 activates the Fanconi anemia DNA repair pathway and limits the efficacy of cisplatin treatment in squamous cell carcinoma.
Nucleic Acids Res
; 44(7): 3204-18, 2016 Apr 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-26819410
13.
Altered glycogen metabolism causes hepatomegaly following an Atg7 deletion.
Cell Tissue Res
; 366(3): 651-665, 2016 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-27553638
14.
Galectin-3 interacts with components of the nuclear ribonucleoprotein complex.
BMC Cancer
; 16: 502, 2016 07 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-27435226
15.
Characterization of the p53 cistrome--DNA binding cooperativity dissects p53's tumor suppressor functions.
PLoS Genet
; 9(8): e1003726, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23966881
16.
Immunosuppressive capabilities of mesenchymal stromal cells are maintained under hypoxic growth conditions and after gamma irradiation.
Cytotherapy
; 17(2): 152-62, 2015 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-25453724
17.
p53 partial loss-of-function mutations sensitize to chemotherapy.
Oncogene
; 41(7): 1011-1023, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34907344
18.
IRF4 deficiency vulnerates B-cell progeny for leukemogenesis via somatically acquired Jak3 mutations conferring IL-7 hypersensitivity.
Cell Death Differ
; 29(11): 2163-2176, 2022 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-35459909
19.
Superior Overall Survival in Patients with Colorectal Cancer, Regular Aspirin Use, and Combined Wild-Type PIK3CA and KRAS-Mutated Tumors.
Cancers (Basel)
; 13(19)2021 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34638442
20.
Evolutionary construction of multiple graph alignments for the structural analysis of biomolecules.
Bioinformatics
; 25(16): 2110-7, 2009 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19286830