Detalhe da pesquisa
1.
HNRNPH1 regulates the neuroprotective cold-shock protein RBM3 expression through poison exon exclusion.
EMBO J
; 42(14): e113168, 2023 07 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-37248947
2.
WINDOW consortium: A path towards increased therapy efficacy against glioblastoma.
Drug Resist Updat
; 40: 17-24, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-30439622
3.
Genome-wide characterisation of Foxa1 binding sites reveals several mechanisms for regulating neuronal differentiation in midbrain dopamine cells.
Development
; 142(7): 1315-24, 2015 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25804738
4.
Genome-wide characterization of Foxa2 targets reveals upregulation of floor plate genes and repression of ventrolateral genes in midbrain dopaminergic progenitors.
Development
; 139(14): 2625-34, 2012 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-22696295
5.
Foxa1 and foxa2 are required for the maintenance of dopaminergic properties in ventral midbrain neurons at late embryonic stages.
J Neurosci
; 33(18): 8022-34, 2013 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23637192
6.
Unravelling cell type-specific responses to Parkinson's Disease at single cell resolution.
Mol Neurodegener
; 19(1): 7, 2024 Jan 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-38245794
7.
Genome-wide CRISPR/Cas9 screen shows that loss of GET4 increases mitochondria-endoplasmic reticulum contact sites and is neuroprotective.
Cell Death Dis
; 15(3): 203, 2024 Mar 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-38467609
8.
Single-cell transcriptomics identifies perturbed molecular pathways in midbrain organoids using α-synuclein triplication Parkinson's disease patient-derived iPSCs.
Neurosci Res
; 195: 13-28, 2023 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-37271312
9.
A genetic variant of the Wnt receptor LRP6 accelerates synapse degeneration during aging and in Alzheimer's disease.
Sci Adv
; 9(2): eabo7421, 2023 01 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-36638182
10.
Mitochondrial and Endoplasmic Reticulum Stress Trigger Triglyceride Accumulation in Models of Parkinson's Disease Independent of Mutations in MAPT.
Metabolites
; 13(1)2023 Jan 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36677037
11.
CRISPR-Cas9 genetic screen leads to the discovery of L-Moses, a KAT2B inhibitor that attenuates Tunicamycin-mediated neuronal cell death.
Sci Rep
; 13(1): 3934, 2023 03 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36894612
12.
Derivation of nociceptive sensory neurons from hiPSCs with early patterning and temporally controlled NEUROG2 overexpression.
Cell Rep Methods
; 2(11): 100341, 2022 11 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-36452863
13.
Cholesterol determines the cytosolic entry and seeded aggregation of tau.
Cell Rep
; 39(5): 110776, 2022 05 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35508140
14.
ER-mitochondria contact sites in neurodegeneration: genetic screening approaches to investigate novel disease mechanisms.
Cell Death Differ
; 28(6): 1804-1821, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33335290
15.
Using Reactome to build an autophagy mechanism knowledgebase.
Autophagy
; 17(6): 1543-1554, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32486891
16.
MicroExonator enables systematic discovery and quantification of microexons across mouse embryonic development.
Genome Biol
; 22(1): 43, 2021 01 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-33482885
17.
The transcription factor BCL11A defines distinct subsets of midbrain dopaminergic neurons.
Cell Rep
; 36(11): 109697, 2021 09 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-34525371
18.
Foxa1 and Foxa2 function both upstream of and cooperatively with Lmx1a and Lmx1b in a feedforward loop promoting mesodiencephalic dopaminergic neuron development.
Dev Biol
; 333(2): 386-96, 2009 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19607821
19.
Development and Application of High-Throughput Single Cell Lipid Profiling: A Study of SNCA-A53T Human Dopamine Neurons.
iScience
; 23(11): 101703, 2020 Nov 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-33196026
20.
Single-Cell Transcriptomics of Parkinson's Disease Human In Vitro Models Reveals Dopamine Neuron-Specific Stress Responses.
Cell Rep
; 33(2): 108263, 2020 10 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-33053338