Detalhe da pesquisa
1.
The kidney releases a nonpolymerizing form of uromodulin in the urine and circulation that retains the external hydrophobic patch domain.
Am J Physiol Renal Physiol
; 322(4): F403-F418, 2022 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35100812
2.
The kidney protects against sepsis by producing systemic uromodulin.
Am J Physiol Renal Physiol
; 323(2): F212-F226, 2022 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35759740
3.
Uromodulin (Tamm-Horsfall protein): guardian of urinary and systemic homeostasis.
Nephrol Dial Transplant
; 35(1): 33-43, 2020 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30649494
4.
Tamm-Horsfall Protein Regulates Mononuclear Phagocytes in the Kidney.
J Am Soc Nephrol
; 29(3): 841-856, 2018 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29180395
5.
Quantitative Three-Dimensional Tissue Cytometry to Study Kidney Tissue and Resident Immune Cells.
J Am Soc Nephrol
; 28(7): 2108-2118, 2017 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-28154201
6.
Tamm-Horsfall Protein Regulates Granulopoiesis and Systemic Neutrophil Homeostasis.
J Am Soc Nephrol
; 26(9): 2172-82, 2015 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-25556169
7.
An intricate network of conserved DNA upstream motifs and associated transcription factors regulate the expression of uromodulin gene.
J Urol
; 192(3): 981-9, 2014 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-24594405
8.
The role of tumor necrosis factor alpha in regulating the expression of Tamm-Horsfall Protein (uromodulin) in thick ascending limbs during kidney injury.
Am J Nephrol
; 40(5): 458-67, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-25503683
9.
Water Loading and Uromodulin Secretion in Healthy Individuals and Idiopathic Calcium Stone Formers.
Clin J Am Soc Nephrol
; 18(8): 1059-1067, 2023 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37256909
10.
Evolving Concepts in Uromodulin Biology, Physiology, and Its Role in Disease: a Tale of Two Forms.
Hypertension
; 79(11): 2409-2418, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-35959659
11.
Different roles of N- and C- termini in the functional activity of FGF21.
J Cell Physiol
; 219(2): 227-34, 2009 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-19117008
12.
Circulating uromodulin inhibits systemic oxidative stress by inactivating the TRPM2 channel.
Sci Transl Med
; 11(512)2019 10 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31578243
13.
FGF-21/FGF-21 receptor interaction and activation is determined by betaKlotho.
J Cell Physiol
; 215(1): 1-7, 2008 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-18064602
14.
FGF-21 as a novel metabolic regulator.
J Clin Invest
; 115(6): 1627-35, 2005 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-15902306
15.
Healthy Women Have Higher Systemic Uromodulin Levels: Identification of Uromodulin as an Estrogen Responsive Gene.
Kidney360
; 4(9): e1302-e1307, 2023 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37340540
16.
pI-shifted insulin analogs with extended in vivo time action and favorable receptor selectivity.
Peptides
; 28(4): 935-48, 2007 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-17328992
17.
Immunofluorescence laser micro-dissection of specific nephron segments in the mouse kidney allows targeted downstream proteomic analysis.
Physiol Rep
; 3(2)2015 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25677553
18.
Decoy receptor 3 (DcR3) is proteolytically processed to a metabolic fragment having differential activities against Fas ligand and LIGHT.
Biochem Pharmacol
; 65(4): 657-67, 2003 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-12566095
19.
Rational design of a fibroblast growth factor 21-based clinical candidate, LY2405319.
PLoS One
; 8(3): e58575, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23536797
20.
Fundamentals of FGF19 & FGF21 action in vitro and in vivo.
PLoS One
; 7(5): e38438, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22675463