Detalhe da pesquisa
1.
Impairment of DNA Methylation Maintenance Is the Main Cause of Global Demethylation in Naive Embryonic Stem Cells.
Mol Cell
; 62(6): 848-861, 2016 06 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-27237052
2.
Compromised Mitotic Fidelity in Human Pluripotent Stem Cells.
Int J Mol Sci
; 24(15)2023 Jul 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-37569309
3.
Impairment of DNA Methylation Maintenance Is the Main Cause of Global Demethylation in Naive Embryonic Stem Cells.
Mol Cell
; 62(6): 983, 2016 06 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-27315559
4.
Okadaic acid inhibits the trichostatin A-mediated increase of human CYP46A1 neuronal expression in a ERK1/2-Sp3-dependent pathway.
J Lipid Res
; 53(9): 1910-9, 2012 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-22693257
5.
Neuronal differentiation alters the ratio of Sp transcription factors recruited to the CYP46A1 promoter.
J Neurochem
; 120(2): 220-9, 2012 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-22060190
6.
Generation and characterization of induced pluripotent stem cell line (IBBISTi004-A) from an Angelman syndrome patient carrying a class II deletion of the maternal chromosome 15q11.2-q13.
Stem Cell Res
; 61: 102757, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35339881
7.
Multi-omic rejuvenation of human cells by maturation phase transient reprogramming.
Elife
; 112022 04 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35390271
8.
Voicing the need to consider sex-specific differences in research.
Dev Cell
; 57(24): 2675-2678, 2022 12 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-36538892
9.
Generation and characterization of induced pluripotent stem cells heterozygous for the Portuguese BRCA2 founder mutation.
Stem Cell Res
; 53: 102364, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-34087993
10.
Generation and characterization of induced pluripotent stem cells from a family carrying the BRCA1 mutation c.3612delA.
Stem Cell Res
; 52: 102242, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33631522
11.
Sp proteins play a critical role in histone deacetylase inhibitor-mediated derepression of CYP46A1 gene transcription.
J Neurochem
; 113(2): 418-31, 2010 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-20096088
12.
Reprogramming of human cells to pluripotency induces CENP-A chromatin depletion.
Open Biol
; 10(10): 200227, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33081635
13.
Glutathione S-transferase pi regulates UV-induced JNK signaling in SH-SY5Y neuroblastoma cells.
Neurosci Lett
; 451(3): 241-5, 2009 Feb 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-19159663
14.
Transcriptional regulation of the human CYP46A1 brain-specific expression by Sp transcription factors.
J Neurochem
; 106(2): 835-49, 2008 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-18445135
15.
Gender Differences in Global but Not Targeted Demethylation in iPSC Reprogramming.
Cell Rep
; 18(5): 1079-1089, 2017 01 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-28147265
16.
MERVL/Zscan4 Network Activation Results in Transient Genome-wide DNA Demethylation of mESCs.
Cell Rep
; 17(1): 179-192, 2016 09 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-27681430
17.
Marked change in the balance between CYP27A1 and CYP46A1 mediated elimination of cholesterol during differentiation of human neuronal cells.
Neurochem Int
; 60(2): 192-8, 2012 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-22185844
18.
Demethylation of the coding region triggers the activation of the human testis-specific PDHA2 gene in somatic tissues.
PLoS One
; 7(6): e38076, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22675509
19.
Chromatin-modifying agents increase transcription of CYP46A1, a key player in brain cholesterol elimination.
J Alzheimers Dis
; 22(4): 1209-21, 2010.
Artigo
em Inglês
| MEDLINE | ID: mdl-20930312