Detalhe da pesquisa
1.
FUS ALS-causative mutations impair FUS autoregulation and splicing factor networks through intron retention.
Nucleic Acids Res
; 48(12): 6889-6905, 2020 07 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32479602
2.
Early microgliosis precedes neuronal loss and behavioural impairment in mice with a frontotemporal dementia-causing CHMP2B mutation.
Hum Mol Genet
; 26(5): 873-887, 2017 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28093491
3.
Frontotemporal dementia causative CHMP2B impairs neuronal endolysosomal traffic-rescue by TMEM106B knockdown.
Brain
; 141(12): 3428-3442, 2018 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30496365
4.
Glycolytic-to-oxidative fiber-type switch and mTOR signaling activation are early-onset features of SBMA muscle modified by high-fat diet.
Acta Neuropathol
; 132(1): 127-44, 2016 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-26971100
5.
PolyGR and polyPR knock-in mice reveal a conserved neuroprotective extracellular matrix signature in C9orf72 ALS/FTD neurons.
Nat Neurosci
; 27(4): 643-655, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38424324
6.
Transcriptome-wide RNA binding analysis of C9orf72 poly(PR) dipeptides.
Life Sci Alliance
; 6(9)2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37438085
7.
Beta-agonist stimulation ameliorates the phenotype of spinal and bulbar muscular atrophy mice and patient-derived myotubes.
Sci Rep
; 7: 41046, 2017 01 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-28117338
8.
Protein arginine methyltransferase 6 enhances polyglutamine-expanded androgen receptor function and toxicity in spinal and bulbar muscular atrophy.
Neuron
; 85(1): 88-100, 2015 Jan 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-25569348
9.
Aberrant Autophagic Response in The Muscle of A Knock-in Mouse Model of Spinal and Bulbar Muscular Atrophy.
Sci Rep
; 5: 15174, 2015 Oct 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-26490709
10.
Androgens affect muscle, motor neuron, and survival in a mouse model of SOD1-related amyotrophic lateral sclerosis.
Neurobiol Aging
; 35(8): 1929-38, 2014 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-24630363
11.
Protein arginine methyltransferase 1 and 8 interact with FUS to modify its sub-cellular distribution and toxicity in vitro and in vivo.
PLoS One
; 8(4): e61576, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23620769