Detalhe da pesquisa
1.
Reshaping the 2-Pyrone Synthase Active Site for Chemoselective Biosynthesis of Polyketides.
Angew Chem Int Ed Engl
; 62(5): e202212440, 2023 01 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-36398563
2.
Increasing Reduction Potentials of Type 1 Copper Center and Catalytic Efficiency of Small Laccase from Streptomyces coelicolor through Secondary Coordination Sphere Mutations.
Angew Chem Int Ed Engl
; 62(52): e202314019, 2023 Dec 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-37926680
3.
Molecular understanding of heteronuclear active sites in heme-copper oxidases, nitric oxide reductases, and sulfite reductases through biomimetic modelling.
Chem Soc Rev
; 50(4): 2486-2539, 2021 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33475096
4.
Heme redox potentials hold the key to reactivity differences between nitric oxide reductase and heme-copper oxidase.
Proc Natl Acad Sci U S A
; 115(24): 6195-6200, 2018 06 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-29802230
5.
A Binuclear CuA Center Designed in an All α-Helical Protein Scaffold.
J Am Chem Soc
; 142(32): 13779-13794, 2020 08 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32662996
6.
Understanding and Modulating Metalloenzymes with Unnatural Amino Acids, Non-Native Metal Ions, and Non-Native Metallocofactors.
Acc Chem Res
; 52(4): 935-944, 2019 04 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-30912643
7.
Manganese and Cobalt in the Nonheme-Metal-Binding Site of a Biosynthetic Model of Heme-Copper Oxidase Superfamily Confer Oxidase Activity through Redox-Inactive Mechanism.
J Am Chem Soc
; 139(35): 12209-12218, 2017 09 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28768416
8.
Enhancing Mn(II)-Binding and Manganese Peroxidase Activity in a Designed Cytochrome c Peroxidase through Fine-Tuning Secondary-Sphere Interactions.
Biochemistry
; 55(10): 1494-502, 2016 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26885726
9.
A designed heme-[4Fe-4S] metalloenzyme catalyzes sulfite reduction like the native enzyme.
Science
; 361(6407): 1098-1101, 2018 09 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-30213908
10.
Why copper is preferred over iron for oxygen activation and reduction in haem-copper oxidases.
Nat Chem
; 9(3): 257-263, 2017 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-28221360