Detalhe da pesquisa
1.
Characterizing the Blood-Stage Antimalarial Activity of Tafenoquine in Healthy Volunteers Experimentally Infected With Plasmodium falciparum.
Clin Infect Dis
; 76(11): 1919-1927, 2023 06 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-36795050
2.
Predicting Optimal Antimalarial Drug Combinations from a Standardized Plasmodium falciparum Humanized Mouse Model.
Antimicrob Agents Chemother
; 67(6): e0157422, 2023 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37133382
3.
Seeking an optimal dosing regimen for OZ439/DSM265 combination therapy for treating uncomplicated falciparum malaria.
J Antimicrob Chemother
; 76(9): 2325-2334, 2021 08 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34179977
4.
Haematological response in experimental human Plasmodium falciparum and Plasmodium vivax malaria.
Malar J
; 20(1): 470, 2021 Dec 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-34930260
5.
Development and evaluation of a new Plasmodium falciparum 3D7 blood stage malaria cell bank for use in malaria volunteer infection studies.
Malar J
; 20(1): 93, 2021 Feb 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-33593375
6.
An in vitro toolbox to accelerate anti-malarial drug discovery and development.
Malar J
; 19(1): 1, 2020 Jan 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31898492
7.
Characterization of Novel Antimalarial Compound ACT-451840: Preclinical Assessment of Activity and Dose-Efficacy Modeling.
PLoS Med
; 13(10): e1002138, 2016 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-27701420
8.
Characterising the blood-stage antimalarial activity of pyronaridine in healthy volunteers experimentally infected with Plasmodium falciparum.
Int J Antimicrob Agents
; 64(1): 107196, 2024 May 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-38734217
9.
First-in-man safety and pharmacokinetics of synthetic ozonide OZ439 demonstrates an improved exposure profile relative to other peroxide antimalarials.
Br J Clin Pharmacol
; 75(2): 524-37, 2013 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-22759078
10.
The global pipeline of new medicines for the control and elimination of malaria.
Malar J
; 11: 316, 2012 Sep 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-22958514
11.
Development of New Strategies for Malaria Chemoprophylaxis: From Monoclonal Antibodies to Long-Acting Injectable Drugs.
Trop Med Infect Dis
; 7(4)2022 Apr 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35448833
12.
PCR correction strategies for malaria drug trials: updates and clarifications.
Lancet Infect Dis
; 20(1): e20-e25, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31540841
13.
Liver Function Test Abnormalities in Experimental and Clinical Plasmodium vivax Infection.
Am J Trop Med Hyg
; 103(5): 1910-1917, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32815508
14.
A Plasmodium vivax experimental human infection model for evaluating efficacy of interventions.
J Clin Invest
; 130(6): 2920-2927, 2020 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32045385
15.
Increased stress associated with head-out plethysmography testing can exacerbate respiratory effects and lead to mortality in rats.
J Pharmacol Toxicol Methods
; 99: 106580, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31085318
16.
Safety, tolerability, and single- and multiple-dose pharmacokinetics of piperaquine phosphate in healthy subjects.
J Clin Pharmacol
; 48(2): 166-75, 2008 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-18199893
17.
Safety, tolerability and pharmacokinetic profile of single and multiple oral doses of arterolane (RBx11160) maleate in healthy subjects.
J Clin Pharmacol
; 54(4): 386-93, 2014 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-24242999
18.
Pharmacokinetics and pharmacodynamics of arterolane maleate following multiple oral doses in adult patients with P. falciparum malaria.
J Clin Pharmacol
; 51(11): 1519-28, 2011 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-21148048