Detalhe da pesquisa
1.
Evolutionary repurposing of a sulfatase: A new Michaelis complex leads to efficient transition state charge offset.
Proc Natl Acad Sci U S A
; 115(31): E7293-E7302, 2018 07 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-30012610
2.
Transition-State Interactions in a Promiscuous Enzyme: Sulfate and Phosphate Monoester Hydrolysis by Pseudomonas aeruginosa Arylsulfatase.
Biochemistry
; 58(10): 1363-1378, 2019 03 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30810299
3.
Balancing Specificity and Promiscuity in Enzyme Evolution: Multidimensional Activity Transitions in the Alkaline Phosphatase Superfamily.
J Am Chem Soc
; 141(1): 370-387, 2019 01 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-30497259
4.
Efficient, crosswise catalytic promiscuity among enzymes that catalyze phosphoryl transfer.
Biochim Biophys Acta
; 1834(1): 417-24, 2013 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-22885024
5.
Solvent induced cooperativity of Zn(II) complexes cleaving a phosphate diester RNA analog in methanol.
Org Biomol Chem
; 10(3): 631-9, 2012 Jan 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-22116167
6.
Cleavage of an RNA model catalyzed by dinuclear Zn(II) complexes containing rate-accelerating pendants. Comparison of the catalytic benefits of H-bonding and hydrophobic substituents.
J Org Chem
; 75(24): 8471-7, 2010 Dec 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-21087029
7.
An immobilized ortho-palladated dimethylbenzylamine complex as an efficient catalyst for the methanolysis of phosphorothionate pesticides.
Inorg Chem
; 48(3): 1183-91, 2009 Feb 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-19105733
8.
Investigation of the effect of oxy bridging groups in dinuclear Zn(II) complexes that catalyze the cleavage of a simple phosphate diester RNA analogue.
Inorg Chem
; 48(23): 11425-33, 2009 Dec 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-19874005
9.
Ultrahigh-throughput discovery of promiscuous enzymes by picodroplet functional metagenomics.
Nat Commun
; 6: 10008, 2015 Dec 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-26639611
10.
Evolution of enzyme catalysts caged in biomimetic gel-shell beads.
Nat Chem
; 6(9): 791-6, 2014 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-25143214
11.
Picoliter cell lysate assays in microfluidic droplet compartments for directed enzyme evolution.
Chem Biol
; 19(8): 1001-9, 2012 Aug 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-22921067
12.
Potentiometric titration of metal ions in ethanol.
Inorg Chem
; 45(19): 7891-902, 2006 Sep 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-16961382
13.
Combination of a dinuclear Zn2+ complex and a medium effect exerts a 10(12)-fold rate enhancement of cleavage of an RNA and DNA model system.
J Am Chem Soc
; 128(50): 16398-405, 2006 Dec 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-17165797